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Title Protein-carbohydrate interactions in infectious diseases / edited by Carole A. Bewley
Published Cambridge, UK : RSC Publishing, ©2006


Description 1 online resource (xiii, 250 pages) : illustrations (some color)
Series RSC biomolecular sciences
RSC biomolecular sciences
Contents 1. Atomic basis of protein-carbohydrate interactions: an overview / Nathan Sharon -- 2. Mycobacterial glycolipids and the host: role of phenolic glycolipid and lipoarabinomannan / G.J. Blaauw and B.J. Appelmelk -- 3. Structure and roles of Pseudomonas aeruginosa lectins / Anne Imberty [and others] -- 4. Protein-carbohydrate interactions in enterobacterial infections / Nathan Sharon and Itzhak Ofek -- 5. GM1 glycomimetics and bacterial enterotoxins / Anna Bernardi [and others] -- 6. Retrocyclins: miniature lectins with potent antiviral activity / Robert I. Lehrer -- 7. C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates / Sandra J. Van Vliet, Christian H. Grün and Yvette Van Kooyk --- 8. Targeting microbial sialic acid metabolism for new drug development / Eric R. Vimr and Susan M. Steenbergen -- 9. Synthetic carbohydrate-based antimalarial vaccines and glycobiology / Alexandra Hölemann and Peter H. Seeberger -- 10. Studies toward a rationally designed conjugate vaccine for cholera using synthetic carbohydrate antigens / Pavol Kováč -- 11. Carbohydrate microarrays for high-throughput analysis of carbohydrate-protein interactions / Injae Shin
Summary Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true for host-pathogen interactions that lead to infectious diseases; as the surfaces of cells and pathogens display complex carbohydrate structures and carbohydrate binding proteins on their surface. Protein-Carbohydrate Interactions in Infectious Disease is part of the Biomolecular Science Series and provides a comprehensive overview of the subject, with contributions from leading experts in the field. Beginning with a general introduction, subsequent sections include: Atomic basis of protein-carbohydrate interactions, Structures and roles of Pseudomonas areuginosa lectins, Protein-carbohydrate interactions in enterobacterial infections, Retrocyclins: miniature lectins with potent antiviral activity, C-type lectin receptors that regulate pathogen recognition through the recognition of carbohydrates, Synthetic carbohydrate-based anti-malarial vaccines and glycobiology. With full colour throughout and an extensive bibliography this book is ideal for researchers interested in the area
Bibliography Includes bibliographical references (pages 243-246) and index
Subject Glycoproteins -- Immunology
Carbohydrates -- Immunology
Proteins -- Immunology
Mycobacterial diseases -- Molecular aspects
Molecular microbiology.
Communicable diseases
Communicable Diseases
Communicable Diseases -- etiology
Lectins -- immunology
Vaccines, Synthetic
MEDICAL -- Clinical Medicine.
SCIENCE -- Chemistry -- Clinical.
Carbohydrates -- Immunology.
Communicable diseases.
Molecular microbiology.
Proteins -- Immunology.
Form Electronic book
Author Bewley, Carole A. (Carole Ann), 1963-
ISBN 9781847555335