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Title Platelet rich plasma in musculoskeletal practice / Nicola Maffulli, editor
Published London : Springer, 2016
Online access available from:
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Description 1 online resource
Contents Preface; About the Editor; Contents; Chapter 1: Contents and Formulations of Platelet Rich Plasma; Content of Platelet-Rich Plasma Preparations; Platelets; Leukocytes; Fibrin; Growth Factors and Cytokines; Platelet-Rich Formulations; Platelet-Rich Plasma (PRP); Leukocyte-Rich PRP (LR-PRP); Leukocyte-Poor PRP (LP-PRP); Platelet-Poor Plasma (PPP); PRP Gel; PPP Gel (Fibrin Glue and Sealant); Activation Procedures; Calcium Chloride and Thrombin Activation; Freeze/Thaw Cycle Activation; In Vivo Collagen Activation; Commercial PRP Systems; PRP Classification Systems
Effect of PRP on the Cellular Environment Fibroblasts; Collagen; Tenocytes; Systemic Effects; Conclusion; References; Chapter 2: Platelet-Rich Plasma in Pain Medicine; Summary; Introduction; PRP Processing; Injection Technique; Ultrasound-Guided Peripheral Blocks; Ultrasound-Guided Anesthetic Blocks for Differential Pain Diagnoses; PRP in Orthopedics and Pain Medicine; Tendons and Ligaments; Muscle; Cartilage; Spine; Glucosamine and Chondroitin; Cell Therapies; Conclusion; References; Chapter 3: PRP: Tips for Application in the Musculoskeletal System; Introduction
PRP Preparation Leukocyte Rich vs. Leukocyte Poor PRP; PRP With or Without RBCs; Platelet Activation and PRP Anti-coagulation; Current Applications; Tendinopathy; Ligament Pathology; Muscle Pathology; Intervertebral Disc and Spine Pathology; Cartilage; Rehabilitation Following PRP Injection; Tips and Concerns; Conclusions; References; Chapter 4: PRP in Tendons and Other Non-bone Tissues; Introduction; Tendons; Achilles Tendinopathy; Patellar Tendinopathy; Lateral Epicondylitis; Rotator Cuff; Plantar Fasciopathy; Knee Osteoarthritis; Conclusion; References
Chapter 5: Platelet Rich Plasma in Articular Cartilage Lesions Physiopathology of Articular Cartilage; Definition of PRP and Sources of Variability; Biological Rationale; Literature on the Clinical Application of PRP; Knee Application; Hip Applications; PRP in Talar Osteochondral Lesions; Discussion; Conclusions; References; Chapter 6: Platelet-Rich Plasma in Knee Osteoarthritis in the Athlete; Introduction; Pathophysiology of Knee Osteoarthritis; Nociception in OA; Clinical Applications of PRP for Joint Osteoarthritis; Current Research and Evidence; Patient Selection; Methods
What Have We Learned? Conclusions and Future Implications; References; Chapter 7: Platelet Rich Plasma in Foot and Ankle Surgery; Introduction; Foot and Ankle Sport Injuries: Epidemiology and Biomechanics; Foot and Ankle: Soft Tissues and Cartilage; PRP: Any Evidence of Effectiveness?; Basic Science; Clinical Applications; Conclusion; References; Chapter 8: Platelet Rich Plasma for Biological Therapy: Applications and Limits; Introduction; Molecular Biology; PRP Preparation; Main Cell Populations Trapped in PRPs; Chemokines, Cytokines & Growth Factors
Summary This book provides an introductory overview of advancements in platelet-rich plasma (PRP), focusing on current technologies and methods, new challenges and controversies, and avenues for further research. With many studies demonstrating a role for PRP in improving response to injury, this book aims to facilitate the application of this rapidly growing treatment option for trauma patients. Platelet Rich Plasma in Musculoskeletal Practice is a highly informative and carefully presented book, providing scientific and clinical insight for specialists who utilize PRP in daily practice, and for readers who are seeking to learn more about this effective injury treatment
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Blood plasma.
Musculoskeletal system -- Diseases -- Molecular aspects.
Platelet-Rich Plasma.
Form Electronic book
Author Maffulli, Nicola, editor
ISBN 9781447172710 (electronic bk.)
144717271X (electronic bk.)