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E-book

Title Airway smooth muscle in asthma and COPD : biology and pharmacology / edited by Kian Fan Chung
Published Chichester ; Hoboken, N.J. : John Wiley & Sons, ©2008

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Description 1 online resource (xiv, 312 pages, 4 unnumbered pages of plates) : illustrations (some color)
Contents Airway Smooth Muscle; Contents; List of Contributors; 1 Biophysical basis of airway smooth muscle contraction and hyperresponsiveness in asthma; 2 Dynamics of cytoskeletal and contractile protein organization: an emerging paradigm for airway smooth muscle contraction; 3 Airway smooth muscle: role in airway constrictor hyperresponsiveness; 4 Airway smooth muscle phenotypic and functional plasticity; 5 Airway smooth muscle proliferation: insights into mechanisms regulating airway smooth muscle mass; 6 Airway smooth muscle bidirectional interactions with extracellular matrix
7 Airway smooth muscle interaction with mast cells8 Airway smooth muscle synthesis of inflammatory mediators; 9 Airway smooth muscle in experimental models; 10 Altered properties of airway smooth muscle in asthma; 11 The airway smooth muscle in chronic obstructive pulmonary disease (COPD); 12 Glucocorticoid actions on airway smooth muscle; 13 B2-Adrenergic receptors: effects on airway smooth muscle; 14 Asthma treatments: effects
Summary In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. . Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. : Authoritative update on key mech
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Respiratory muscles -- Physiology
Smooth muscle -- Physiology
Smooth muscle -- Molecular aspects
Respiratory agents.
Respiratory organs -- Diseases -- Treatment
Respiratory therapy.
Asthma -- physiopathology
Pulmonary Disease, Chronic Obstructive -- physiopathology
Muscle, Smooth -- drug effects
Muscle, Smooth -- physiopathology
Respiratory System -- drug effects
Respiratory System -- physiopathology
Respiratory System Agents
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Respiratory agents
Respiratory muscles -- Physiology
Respiratory organs -- Diseases -- Treatment
Respiratory therapy
Smooth muscle -- Physiology
Form Electronic book
Author Chung, K. Fan, 1951-
ISBN 9780470754214
0470754214
9780470060667
0470060662