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Title Kawasaki disease : current understanding of the mechanism and evidence-based treatment / Ben Tsutomu Saji, Jane W. Newburger, Jane C. Burns, Masato Takahashi, editors
Published Japan : Springer, [2016]


Description 1 online resource (xix, 552 pages) : illustrations (some color)
Contents Foreword; Preface; References; Contents; Part I: Basic Research; The History of Kawasaki Disease: A Personal Perspective; Introduction; The Era of Clinical Description and Pathologic Recognition: 1960-1984; Back to the Future: 1871-1984 and Other Riddles of KD; The Era of Enhanced Discovery and International Collaboration: 1984-2015; References; Histopathology of Coronary Arteritis in Acute Kawasaki Disease and Murine Systemic Vasculitis Induced by Candida Albicans Cell ... ; Introduction; Histopathological Characteristics of Coronary Arteritis in Acute KD
The C. Albicans Cell Wall Polysaccharide-Induced Murine Vasculitis ModelModel Development and Description of the Vasculitis-Inducing Agent; Histopathological Characteristics of C. Albicans Polysaccharide-Induced Murine Vasculitis; Relationship of Mouse Genetic Background to Cytokines and Vasculitis; Response of C. Albicans Polysaccharide-Induced Vasculitis to Treatment; References; Histopathological Characteristics of Noncardiac Organs in Kawasaki Disease; Introduction; Brief Overview of Systemic Vascular Lesions in KD; Histological Changes in Noncardiac Organs in KD; References
Identification of Novel Kawasaki Disease Susceptibility Genes by Genome-Wide Association StudiesIntroduction; History of the Genetic Study of KD; Genomic Studies of KD in the Post-Genomic era; ITPKC; CASP3; FCGR2A; BLK; CD40; HLA class II; Current Understandings and Recognition; Recent Advances; References; Immunological Abnormalities and Use of Biomarkers and Cytokines to Predict the Severity of Kawasaki Disease; Introduction; KD and Hypercytokinemia; Which Cytokines/Biomarkers Best Predict KD Severity?; Conclusions; References; Pathophysiology of Kawasaki Disease; Introduction; History
The Three Linked Pathological Processes of KD VasculopathyRecent Advances in Etiological, Genomic, and Gene Expression Studies; Conclusions; References; Update on Pathogenesis: Lessons Learned from Animal Models of Disease; Introduction; T-Cell Activation and Survival and the Role of Costimulation; Murine Models of KD; References; The Climate-KD Link; References; Kawasaki Disease Shock Syndrome; Introduction; Incidence and Demographics; Mechanisms; Clinical Course and Treatment; Differential Diagnosis; Future Perspectives; References; Future Directions in Kawasaki Disease Research
Advances in TreatmentAdvances in Genetics; Advances in Biomarkers and Diagnostic Tests; Advances in Understanding Long-Term Outcomes; References; Part II: Epidemiology; Epidemiologic Perspectives; Historical Perspective; KD Surveillance: Moving Forward; KD Surveillance: Prescription for the Future; References; Update on Nationwide Surveys and Epidemiologic Characteristics of Kawasaki Disease in Japan; Introduction; Methods of the Nationwide Surveys; Results of Nationwide Surveys; What We Have Learned from the Descriptive Epidemiology; Conclusions; References
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed September 1, 2016)
Subject Mucocutaneous lymph node syndrome.
Mucocutaneous lymph node syndrome -- Treatment
Mucocutaneous Lymph Node Syndrome -- physiopathology
Mucocutaneous Lymph Node Syndrome -- therapy
Evidence-Based Medicine -- methods
Cardiovascular medicine.
Paediatric medicine.
MEDICAL -- Gynecology & Obstetrics.
Mucocutaneous lymph node syndrome
Form Electronic book
Author Saji, Ben Tsutomu, editor
Newburger, Jane W., editor.
Burns, Jane C., editor
Takahashi, Masato, 1933- editor.
ISBN 9784431560395