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Title Oral wound healing : cell biology and clinical management / edited by Hannu Larjava
Published Hoboken : John Wiley & Sons, 2012


Description 1 online resource (428 pages)
Contents Oral Wound Healing: Cell Biology and Clinical Management; Contents; Contributors; Preface; 1 Oral Wound Healing: An Overview; Clotting and inflammation (chapters 2, 3 and 4); Re-epithelialization and granulation tissue formation (chapters 5 and 6); Angiogenesis (chapter 7); Healing of extraction sockets (chapter 8); Flap design for periodontal wound healing (chapter 9); Regeneration of periodontal tissues (chapters 10 and 11); Osteointegration and soft tissue healing around dental implants (chapter 12); The pulp healing process (chapter 13); Dermal wound healing and burn wounds (chapter 14)
Healing of large dentofacial defects (chapter 15)References; 2 Hemostasis, Coagulation and Complications; Introduction; Primary hemostasis; Secondary hemostasis and the coagulation system; Tertiary hemostasis; Tissue factor; Von willebrand factor; Other coagulation factors; Cell-centric model of hemostasis: from initiation to propagation; The procoagulant membrane; Membrane particles; Endothelium and hemostasis; Pro- and anticoagulant functions; Platelets; Coagulation and wound healing; Limitations of the waterfall cascade model and screening laboratory tests
Implications for laboratory testsPre-surgical evaluation to prevent bleeding problems; Medical history; Diet and herbal supplements; Clinical examination; Presurgical planning; Control of intra-operative/primary bleeding; Post-operative/secondary bleeding; Conclusions; References; 3 Inflammation and Wound Healing; Introduction; The innate immune response in wounds; Inflammatory cell infiltration into wounds; Inflammatory cell function in wounds; Neutrophils; Mast cells; Macrophages; T lymphocytes; Gamma delta T-cells or dentritic epidermal T-cells (DETCs); Cytokines and chemokines in wounds
Interleukin-1 (IL-1)Interleukin-6 (IL-6); Interleukin-8 (IL-8 or CXCL8); Tumor necrosis factor (TNF alpha); Macrophage chemoattractant protein (MCP-1 or CCL2); Interferon inducible protein 10 (IP-10 or CXCL10); Stromal cell-derived factor (SDF-1 or CXCL12); Transforming growth factor-beta (TGF-b); Inflammation in oral mucosal wounds; Inflammation in fetal wounds; Role of inflammation in keloids; Inflammation and diabetic wounds; Conclusions; References; 4 Specialized Pro-resolving Lipid Derived Fatty Acid Mediators: Wiring the Circuitry of Effector Immune Homeostasis
Inflammation: the cardinal signsComplete resolution and tissue homeostasis is the ideal outcome of acute inflammation; Lipoxins, resolvins, protectins and maresins: semper vigilantes of anti-inflammation and pro-resolution; Lipoxins; Resolvins; Protectins; Maresins; Resolution of inflammation is an actively regulated process in vivo; Resolvins and protectins are protective in experimental models of inflammatory diseases; Specialized pro-resolving lipid mediators in oral medicine: restoration of tissue homeostasis in experimental periodontitis; Resolution and wound healing
Summary Oral Wound Healing: Cell Biology and Clinical Management brings experts from around the world together to provide an authoritative reference on the processes, principles and clinical management of wound healing in the oral mucosa. Promoting a thorough understanding of current research on the topic, this new resource draws together thinking on the basic biological processes of wound healing in the oral environment, as well as providing more detailed information and discussion on processes such as inflammation, reepithelialization and angiogenesis. Beyond this, the book goes on to examine topics
Notes Anti-inflammation vs. Pro-resolution
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Periodontal disease -- Treatment
Mouth -- Wounds and injuries
Mouth -- Surgery.
Wound healing.
Periodontal Diseases -- rehabilitation
Mouth -- injuries
Oral Surgery Procedures -- rehabilitation
Wound Healing
MEDICAL -- Dentistry -- Periodontics.
Mouth -- Surgery
Mouth -- Wounds and injuries
Periodontal disease -- Treatment
Wound healing
Form Electronic book
Author Larjava, Hannu.
ISBN 9781118219638