| Description |
1 online resource (xvi, 212 pages) : illustrations |
| Series |
Springer theses |
|
Springer theses.
|
| Contents |
Electron Paramagnetic Resonance Theory -- The Functional Structure of Human Serum Albumin -- Copper Complexes of Star-Shaped Cholic Acid Oligomers with 1,2,3-Triazole Moieties -- Nano-Inhomogeneities in Structure and Reactivity of Thermoresponsive Hydrogels -- Thermoresponsive Spin-Labeled Hydrogels as Separable DNP Polarizing Agents -- Local Nanoscopic Heterogeneities in Thermoresponsive Dendronized Polymers |
| Summary |
In his thesis, Matthias Junk takes an innovative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure - a consequence of the protein's adaptability to host various endogenous compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nanoscale. These heterogeneities bear consequences for the material's hosting properties and enable unforeseen complex catalytic functionalities |
| Analysis |
Chemistry |
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Spectroscopy |
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Chemistry, Physical organic |
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Polymers |
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Polymer Sciences |
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Spectroscopy/Spectrometry |
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Soft and Granular Matter, Complex Fluids and Microfluidics |
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Physical Chemistry |
| Notes |
"Doctoral thesis accepted by Johannes Gutenberg-Universität Mainz, Mainz, Germany." |
|
Ph. D. Johannes Gutenberg-Universität Mainz |
| Bibliography |
Includes bibliographical references |
| Subject |
Electron paramagnetic resonance spectroscopy.
|
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Molecule-molecule collisions.
|
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Electron Spin Resonance Spectroscopy
|
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SCIENCE -- Chemistry -- Analytic.
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Science des matériaux.
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Chimie.
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Electron paramagnetic resonance spectroscopy
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Molecule-molecule collisions
|
| Genre/Form |
dissertations.
|
|
Academic theses
|
|
Academic theses.
|
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Thèses et écrits académiques.
|
| Form |
Electronic book
|
| ISBN |
9783642251351 |
|
3642251358 |
|
