| Description |
1 online resource (xvi, 684 pages) : illustrations (some color) |
| Contents |
Human genome variation: Disease, drug response, and clinical phenotypes. Session introduction / I. Kohane [and others] -- A stability based method for discovering structure in clustered data / A. Ben-Hur, A. Elisseeff, and I. Guyon -- Singular value decomposition regression models for classification of tumors from microarray experiments / D. Ghosh -- An automated computer system to support ultra high throughput SNP genotyping / J. Heil [and others] -- Inferring genotype from clinical phenotype through a knowledge based algorithm / B.A. Malin and L.A. Sweeney -- A cellular automata approach to detecting interactions among single-nucleotide polymorphisms in complex multifactorial diseases / J.H. Moore and L.W. Hahn -- Ontology development for a pharmacogenetics knowledge base / D.E. Oliver [and others] -- A SOFM approach to predicting HIV drug resistance / R.B. Potter and S. Draghici -- Automating data acquisition into ontologies from pharmacogenetics relational data sources using declarative object definitions and XML / D.L. Rubin [and others] -- On a family-based haplotype pattern mining method for linkage disequilibrium mapping / S. Zhang [and others] -- Genome-wide analysis and comparative genomics. Session introduction / I. Dubchak, L. Pachter, and L. Wei -- Scoring pairwise genomic sequence alignments / F. Chiaromonte, V.B. Yap, and W. Miller -- Structure-based comparison of four eukaryotic genomes / M. Cline [and others] -- Constructing comparative genome maps with unresolved marker order / D. Goldberg, S. McCouch, and J. Kleinberg -- Representation and processing of complex DNA spatial architecture and its annotated genomic content / R. Gherbi and J. Herisson -- Pairwise RNA structure comparison with stochastic context-free grammars / I. Holmes and G.M. Rubin -- Estimation of genetic networks and functional structures between genes by using Bayesian networks and nonparametric regression / S. Imoto, T. Goto and S. Miyano -- Automatic annotation of genomic regulatory sequences by searching for composite clusters / O.V. Kel-Margoulis [and others] -- EULER-PCR: Finishing experiments for repeat resolution / Z. Mulyukov and P.A. Pevzner -- The accuracy of fast phylogenetic methods for large datasets / L. Nakhleh [and others] -- Pre-mRNA secondary structure prediction aids splice site prediction / D.J. Patterson, K. Yasuhara, and W.L. Ruzzo -- Finding weak motifs in DNA sequences / S.-H. Sze, M.S. Gelfand, and P.A. Pevzner -- Evidence for sequence-independent evolutionary traces in genomics data / W. Volkmuth, and N. Alexandrov -- Multiple genome rearrangement by reversals / S. Wu and X. Gu -- High speed homology search with FPGAs / Y. Yamaguchi, T. Maruyama, and A. Konagaya -- Expanding proteomics to glycobiology. Session introduction / C.-W. von der Lieth -- Glycosylation of proteins: A computer based method for the rapid exploration of comformational space of N-glycans / A. Bohne and C.-W. von der Lieth -- Data standardisation in glycoSuiteDB / C.A. Cooper [and others] -- Prediction of glycosylation across the human proteome and the correlation to protein function / R. Gupta and S. Brunak -- Literature data mining for biology. Session introduction / L. Hirschman [and others] -- Mining MEDLINE: Abstracts, sentences, or phrases? / J. Ding [and others] -- Creating knowledge repositories from biomedical reports: The MEDSYNDIKATE text mining system / U. Hahn, M. Romacker, and S. Schulz -- Filling preposition-based templates to capture information from medical abstracts / G. Leroy and H. Chen -- Robust relational parsing over biomedical literature: Extracting inhibit relations / J. Pustejovsk [and others] -- Predicting the sub-cellular location of proteins from text using support vector machines / B.J. Stapley, L.A. Kelley, and M.J.E. Sternberg -- A thematic analysis of the AIDS literature / W.J. Wilbur |
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Genome, pathway and interaction bioinformatics. Session introduction / P. Karp, P. Romero, and E. Neumann -- Pathway logic: Symbolic analysis of biological signaling / S. Eker [and others] -- Towards the prediction of complete protein-protein interaction networks / S.M. Gomez and A. Rzhetsky -- Identifying muscle regulatory elements and genes in the nematode caenorhabditis elegans / D. Guhathakurta [and others] -- Combining location and expression data for principled discovery of genetic regulatory network models / A.J. Hartemink [and others] -- The ERATO systems biology workbench: Enabling interaction and exchange between software tools for computational biology / M. Hucka [and others] -- Genome-wide pathway analysis and visualization using gene expression data / M.P. Kurhekar [and others] -- Exploring gene expression data with class scores / P. Pavlidis, D.P. Lewis, and W.S. Noble -- Guiding revision of regulatory models with expression data / J. Shrager, P. Langley, and A. Pohorille -- Discovery of causal relationships in a gene-regulation pathway from a mixture of experimental and observational DNA microarray data / C. Yoo, V. Thorsson, and G.F. Cooper -- Phylogenetic genomics and genomic phylogenetics. Session introduction / S. Stanley and B.A. Salisbury -- Shallow genomics, phylogenetics, and evolution in the family drosophilidae / M. Zilversmit P. O'Grady, and R. Desalle -- Fast phylogenetic methods for the analysis of genome rearrangement data: An empirical study / L.-S. Wang [and others] -- Vertebrate phylogenomics: Reconciled trees and gene duplications / R.D.M. Page and J.A. Cotton -- Proteins: Structure, function and evolution. Session introduction / P. Clote, G.J.P. Naylor, and Z. Yang -- Screened charge electrostatic model in protein-protein docking simulations / J. Fernandez-Redo, M. Totrov, and R. Abagyan -- The spectrum kernel: A string kernel for SVM protein classification / C. Leslie, E. Eskin, and W.S. Noble -- Detecting positively selected amino acid sites using posterior predictive P- values / R. Nielsen and J.P Huelsenbeck -- Improving sequence alignments for intrinsically disordered proteins / P. Radivojac [and others] -- ab initio folding of multiple-chain proteins / J.A. Saunders, K.D. Gibson, and H.A. Scheraga -- Investigating evolutionary lines of least resistance using the inverse protein-folding problem / J. Schonfeld [and others] -- Using evolutionary methods to study G-protein coupled receptors / O. Soyer [and others] -- Progress in predicting protein function from structure: Unique features of O-glycosidases / E.W. Stawiski [and others] -- Support vector machine prediction of signal peptide cleavage site using a new class of kernels for strings / J.-P. Vert -- Constraint-based hydrophobic core construction for protein structure prediction in the face-centered-cubic lattice / S. Will -- Detecting native protein folds among large decoy sets with hydrophobic moment profiling / R. Zhou and B.D. Silverman |
| Summary |
The Pacific Symposium on Biocomputing brings together key researchers from the international biocomputing community. It is designed to be maximally responsive to the need for critical mass in subdisciplines within biocomputing. This book contains peer-reviewed articles in computational biology |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Biology -- Mathematical models -- Congresses
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Biology -- Computer simulation -- Congresses
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Molecular biology -- Mathematical models -- Congresses
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Molecular biology -- Computer simulation -- Congresses
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NATURE -- Reference.
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SCIENCE -- Life Sciences -- General.
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SCIENCE -- Life Sciences -- Biology.
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Biology -- Computer simulation
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Biology -- Mathematical models
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Molecular biology -- Computer simulation
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Molecular biology -- Mathematical models
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| Genre/Form |
Conference papers and proceedings
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| Form |
Electronic book
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| Author |
Altman, Russ.
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| ISBN |
9789812799623 |
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9812799621 |
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