| Description |
1 online resource (xv, 548 pages) : illustrations (some color) |
| Contents |
Biomolecular networks: from analysis to synthesis. Session introduction / Gil Alterovitz [and others]. Stochastic transient analysis of biochemical systems and its application to the design of biochemical logic gates / Bin Cheng and Marc Riedel. Data-driven ontologies / James C. Costello [and others]. Identification of discriminating biomarkers for human disease using integrative network biology / Joel T. Dudley and Atul J. Butte. Learning the structure of protein-protein interaction networks / Oleksii Kuchaiev and Nataša Pržulj. Inference of functional networks of condition-specific response -- a case study of quiescence in yeast / Sushmita Roy [and others]. Learning cyclic signaling pathway structures while minimizing data requirements / K. Sachs [and others]. Context-specific gene regulations in cancer gene expression data / Ina Sen [and others]. Querying parse tree database of Medline text to synthesize user-specific biomolecular networks / Luis Tari [and others]. Pairwise alignment of interaction networks by fast identification of maximal conserved patterns / Wenhong Tian and Nagiza F. Samatova -- Computational challenges in comparative genomics: gene family evolution, ancestral genome reconstruction, and applications to human genetics. Session introduction / Bernard M.E. Moret [and others]. Identifying parent-daughter relationships among duplicated genes / Mira V. Han and Matthew W Hahn. A parsimony approach to analysis of human segmental duplications / Crystal L. Kahn and Benjamin J. Raphael. An exact solver for the DCJ median problem / Meng Zhang, William Arndt, and Jijun Tang. Inferring genome-wide mosaic structure / Qi Zhang [and others]. Simultaneous history reconstruction for complex gene clusters in multiple species / Yi Zhang [and others] -- Dynamics of biological networks. Session introduction / Tanya Y. Berger-Wolf, Teresa M. Przytycka, and Mona Singh. Dense graphlet statistics of protein interaction and random networks / R. Colak [and others]. Reverse engineering the evolution of protein interaction networks / Todd A. Gibson and Debra S. Goldberg. Identifying dynamic network modules with temporal and spatial constraints / Ruoming Jin [and others]. Efficient and robust prediction algorithms for protein complexes using Gomory-Hu trees / A. Mitrofanova, M. Farach-Colton, and B. Mishra. Parameter estimation of in silico biological pathways with particle filtering towards a petascale computing / Kazuyuki Nakamura [and others]. From ODES to language-based, executable models of biological systems / A. Palmisano, I. Mura, and C. Priami. Unraveling dynamic activities of autocrine pathways that control drug-response transcriptome networks / Yoshinori Tamada [and others]. Dissecting the interface between signaling and transcriptional regulation in human B cells / Kai Wang [and others] -- Emerging challenges in multi-scale modeling in biology. Session introduction / Roy Kerckhoffs [and others]. Finite element analysis of drug electrostatic diffusion: inhibition rate studies in Nl neuraminidase / Yuhui Cheng, Michael J. Holst, and J.A. McCammon. Multi-scale modeling of the human vertebral body: comparison of micro-CT based high-resolution and continuum-level models / Senthil K. Eswaran [and others]. Advances in semantic representation for multiscale biosimulation: a case study in merging models / Maxwell Lewis Neal [and others]. Integration of angiogenesis modules at multiple scales: from molecular to tissue / Amina A. Qutub [and others]. Towards computational modeling of excitation-contraction coupling in cardiac myocytes: reconstruction of structures and proteins from confocal imaging / Frank B. Sachse [and others]. A multiscale approach to sampling nascent peptide chains in the ribosomal exit tunnel / V.A. Voelz, P. Petrone, and V.S. Pande -- Knowledge-driven analysis and data integration for high-throughput biological data. Session introduction / Michael Ochs [and others]. Characterization of unknown adult stem cell samples by large scale data integration and artificial neural networks / G. Bidaut and C.J. Stoeckert Jr. Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies / William S. Bush, Scott M. Dudek, and Marylyn D. Ritchie. Interpreting genetics of gene expression: integrative architecture in bioconductor / V.J. Carey and R. Gentleman. High throughput interaction data reveals degree conservation of hub proteins / A. Fox, D. Taylor, and D.K. Slonim. Unison: an integrated platform for computational biology discovery / Reece K. Hart and Kiran Mukhyala. TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees / Feng Pan [and others]. Improving the efficiency of biomarker identification using biological knowledge / John H. Phan [and others]. Towards a cytokine-cell interaction knowledgebase of the adaptive immune system / Shai S. Shen-Orr [and others]. A Bayesian integration model of high-throughput proteomics and metabolomics data for improved early detection of microbial infections / Bobbie-Jo M. Webb-Robertson [and others] -- Molecular bioinformatics for disease. Session introduction / Yves A. Lussier [and others]. Molecular interaction network based discovery of master regulator genes / Andrea Califano. Supervised classification of array CGH data with HMM-based feature selection / Anneleen Daemen [and others]. Inferring disease-related pathways using a probabilistic epistasis model / P.N. Kanabar [and others]. Combining mutual information with structural analysis to screen for functionally important residues in influenza hemagglutinin / Peter M. Kasson and Vijay S. Pande. Master regulators used as breast cancer metastasis classifier / Wei Keat Lim, Eugenia Lyashenko, and Andrea Califano. Prediction of interactions between HIV -1 and human proteins by information integration / Oznur Tastan [and others]. FastChi: an efficient algorithm for analyzing gene-gene interactions / Xiang Zhang, Fei Zou, and Wei Wang. Open science: tools, approaches, and implications / Cameron Neylon and Shirley Wu. Post-transcriptional gene regulation: RNA-protein interactions, RNA processing, mRNA stability and localization / Benjamin Blencowe [and others] |
| Summary |
The Pacific Symposium on Biocomputing (PSB) 2009 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2009 will be held on January 5-9, 2009 in Kamuela, Hawaii. Tutorials will be offered prior to the start of the conference |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Biology -- Mathematical models -- Congresses
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Molecular biology -- Mathematical models -- Congresses
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Molecular biology -- Computer simulation -- Congresses
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NATURE -- Reference.
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SCIENCE -- Life Sciences -- General.
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SCIENCE -- Life Sciences -- Biology.
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Biology -- Mathematical models
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Molecular biology -- Computer simulation
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Molecular biology -- Mathematical models
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| Genre/Form |
Conference papers and proceedings
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| Form |
Electronic book
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| Author |
Altman, Russ.
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| ISBN |
9789812836939 |
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9812836934 |
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