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Book Cover
E-book
Author Elschner, Mandy

Title BSL3 and BSL4 Agents
Edition 2nd ed
Published Hoboken : John Wiley & Sons, 2012

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Description 1 online resource (401 pages)
Contents BSL3 and BSL4 Agents; 4.5 Clinical and Pathological Findings in Animals; Contents; Acknowledgment; Preface; List of Contributors; Part A Pathogens; Part I Bacteria; 1 Bacillus anthracis: Anthrax; 1.1 Introduction; 1.2 Characteristics of the Agent; 1.3 Diagnosis; 1.3.1 Phenotypical Identification; 1.3.2 Growth Characteristics; 1.3.3 Antibiotic Resistance; 1.3.4 Phage Testing and Biochemistry; 1.3.5 Antigen Detection; 1.3.6 Molecular Identification; 1.3.6.1 Virulence Plasmid pXO1; 1.3.6.2 Virulence Plasmid pXO2; 1.3.7 Chromosome; 1.3.8 MLVA, SNR, and SNP Typing; 1.3.9 Serological Investigations
1.4 Pathogenesis; 1.4.1 Animals; 1.4.2 Humans; 1.5 Clinical and Pathological Findings; 1.5.1 Oropharyngeal Anthrax; 1.5.2 Abdominal or Intestinal Anthrax; 1.5.3 Inhalational or Pulmonary Anthrax; 1.6 Epidemiology; 1.7 Conclusion; References; 2 Brucella Species: Brucellosis; 2.1 Introduction; 2.2 Characteristics of the Agent; 2.3 Diagnosis; 2.3.1 Immunological Approaches; 2.3.2 Polymerase Chain Reaction Assays; 2.4 Pathogenesis; 2.5 Clinical and Pathological Findings; 2.6 Epidemiology, Molecular Typing, and Control Strategies; 2.6.1 Epidemiology; 2.6.2 Molecular Typing Methods
2.6.3 Control Strategies; 2.7 Conclusions; References; 3 Burkholderia mallei: Glanders; 3.1 Introduction; 3.2 Characteristics of the Agent; 3.3 Diagnosis; 3.3.1 Cultural Identification; 3.3.2 Molecular Based Methods; 3.3.3 Antigen Detection; 3.3.4 Serology; 3.4 Clinical and Pathological Findings in Humans; 3.5 Clinical and Pathological Findings in Animals; 3.6 Epidemiology; 3.7 Molecular Typing; 3.8 Conclusions; References; 4 Burkholderia pseudomallei: Melioidosis; 4.1 Introduction; 4.2 Characteristics of the Agent; 4.3 Diagnosis; 4.3.1 Cultural Identification; 4.3.2 Antigen Detection
4.3.3 Molecular Based Methods; 4.3.4 Serology; 4.4 Clinical and Pathological Findings in Humans; 4.6 Epidemiology; 4.6.1 Molecular Typing; 4.7 Conclusions; References; 5 Coxiella burnetii: Q Fever; 5.1 Introduction; 5.2 Characteristics of the Agent; 5.3 Diagnosis; 5.3.1 Direct Detection; 5.3.2 C. burnetii Cultivation; 5.3.3 Detection of C. burnetii Specific DNA; 5.3.4 Serology; 5.4 Pathogenesis; 5.5 Clinical and Pathological Findings; 5.5.1 Acute Q Fever; 5.5.2 Chronic Q Fever; 5.6 Epidemiology, Including Molecular Typing; 5.6.1 Plasmid Types; 5.6.2 RFLP; 5.6.3 IS1111 Typing
5.6.4 Multispacer Sequence Typing; 5.6.5 MLVA Typing; 5.7 Conclusion; References; 6 Francisella tularensis: Tularemia; 6.1 Introduction; 6.2 Characteristics of the Agent; 6.3 Diagnosis; 6.3.1 Serology; 6.3.2 Direct Isolation; 6.3.3 Phenotypical Characteristics; 6.3.4 Molecular Biology Tools for Identification; 6.4 Pathogenesis; 6.5 Clinical and Pathological Findings; 6.5.1 Animals; 6.5.2 Humans; 6.6 Epidemiology and Molecular Typing; 6.7 Conclusion; References; 7 Yersinia pestis: Plague; 7.1 Introduction; 7.2 Characteristics of the Agent; 7.2.1 The Plague Bacterium: Yersinia pestis 88
7.2.1.1 Yersinia pestis Microbiology
Summary In one handy book, this reference gathers all the necessary information on 14 of the most commonly used dangerous groups of pathogens in biosafety level 3 and 4 laboratories. All the chapters are uniformly structured, with a brief overview of the microbiology, pathology, epidemiology and detection methods for each group. In addition, a whole chapter is devoted to the special biosafety requirements, disinfection, decontamination protocols, accident literature and accident procedures, as well as treatment options for all the organisms. This chapter is clearly marked and easy to find when opening
Notes Print version record
Subject Pathogenic microorganisms -- Analysis
Pathogenic microorganisms -- Detection.
Bacterial diseases -- Epidemiology
Bacterial diseases -- Microbiology
Molecular epidemiology.
Biotechnology -- Safety measures
Biological decontamination.
Molecular Epidemiology
Bacterial diseases -- Epidemiology
Biological decontamination
Biotechnology -- Safety measures
Molecular epidemiology
Pathogenic microorganisms -- Detection
Form Electronic book
Author Cutler, Sally
Weidmann, Manfred
Butaye, Patrick
ISBN 9783527645107
3527645101