| Description |
1 online resource |
| Contents |
1. The origins of mouse genetics and the discovery of the T-locus; 2. The evolutionary modern synthesis, t-haplotypes in the wild, and reproductive isolation; 3. Linkage studies, cytogenetics, and the discovery that t-haplotypes consist of a series of inversions--an over-the-Century Project; 4. Developmental genetics and recessive t-lethals; 5. More population genetics with particular attention to the effects of t-allele mediated transmission ratio distortion; 6. Mutation studies including those targeting the T/t-complex--a century long project; 7. Immunogenetics and the failed search for t-antigens-from mid-century and continuing to it's end; 8. Gametogenesis and the genetics of gametes, including t-haplotype segregation distortion; 9. The cloning era and the cloning of Brachury and other T/t complex genes; 10. X-inactivation, epigenetics, and imprinting, including of the T/t complex; 11. Sex determination, sex differentiation, and the Y chromosome--a mostly last quarter of the century effort; 12. Pharmacogenetics--a mostly last half of the century effort; Book Bibliography |
| Subject |
Mice -- Genetics -- History -- 20th century
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Mice -- Genetic engineering -- History -- 20th century
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Transgenic mice -- History -- 20th century
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Mice -- Genetic engineering
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Mice -- Genetics
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Transgenic mice
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| Genre/Form |
History
|
| Form |
Electronic book
|
| ISBN |
9780128240175 |
|
0128240172 |
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