Title Case of the Frozen Addicts : How the Solution of a Medical Mystery Revolutionized the Understanding of Parkinson's Disease

Published IOS Press, 2013

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Description 1 online resource Contents Title Page; Contents; Authors' Note; Prologue; Part One; All in the Mind; Drugs by Design; The Forgotten Case; Brain Damage; Research Wars; A New Start for Parkinson's Disease; Starting Over; Fame and Misfortune; Side Effects; The Cause; To Catch a Chemist; Trail of Ironies; New Treatments; Part Two; Mending the Brain; Miracles; Nemesis; Doing the Unthinkable; Embryonic Conflicts; The Long Journey; Out on a Limb; The Turning Point; Going Public; Unending Quest; Epilogue; Additional material for 2014 edition; What's New in Parkinson's Disease Research?; Acknowledgments; About the authors Summary <![CDATA[In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously "frozen" patients - young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson's disease, administered L-dopa - the only known effective treatment - and "unfroze" his patient. Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an ar Notes Print version record Subject Parkinson's disease -- Case studies Methylphenyltetrahydropyridine -- Physiological effect Designer drugs -- Toxicology Fetal tissues -- Transplantation -- Case studies Parkinson's disease -- Animal models Designer drugs -- Toxicology. Fetal tissues -- Transplantation. Methylphenyltetrahydropyridine -- Physiological effect. Parkinson's disease. Parkinson's disease -- Animal models. Genre/Form Case studies. Form Electronic book ISBN 1306460883 9781306460880

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