| Description |
1 online resource (x, 259 pages) : illustrations (some color) |
| Series |
Methods in Molecular Biology, 1940-6029 ; 1277 |
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Methods in molecular biology (Clifton, N.J.) ; v. 1277. 1064-3745
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| Contents |
Metabonomics : analytical techniques and associated chemometrics / Jacob T. Bjerrum -- Sample collection and preparation of biofluids and extracts for NMR spectroscopy / Gwénaëlle Le Gall -- NMR sprectroscopy of biofluids and extracts / Gwénaëlle Le Gall -- High-resolution magic-angle-spinning NMR spectroscopy of intact tissue / Guro F. Giskeødegård, Maria D. Cao, and Tone F. Bathen -- Sample collection and preparation of biofluids and extracts for liquid chromatography-mass spectrometry / Peiyuan Yin [and three others] -- Liquid chromatography-mass spectrometry of biofluids and extracts / Xinjie Zhao [and three others] -- Sample collection and preparation of biofluids and extracts for gas chromatography-mass spectrometry / Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, and Najeh M. Kharbatia -- Gas chromatography-mass spectrometry of biofluids and extracts / Abdul-Hamid M. Emwas [and three others] -- Capillary electrophoresis-mass spectrometry / Masataka Wakayama, Akiyoshi Hirayama, and Tomoyosji Soga -- Preprocessing of raw metabonomic data / Riyas Vettukattil -- Extracting meaningful information from metabonomic data using multivariate statistics / Max Bylesjö -- Combining metabonomics and other -omics data / Mattias Rantalainen -- The strengths and weaknesses of NMR-spectroscopy and mass spectrometry with particular focus on metabolomics research / Abdul-Hamid M. Emwas -- Metabonomics and drug development / Pranov Ramana [and three others] -- Metabonomics and toxicology / Liang Zhao and Thomas Hartung -- Metabonomics and diagnostics / Lucy C. Hicks, Simon J.L. Ralphs, and Horace R.T. Williams -- Metabonomics and systems biology / Vicky De Preter |
| Summary |
Annotation This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful "Methods in Molecular Biology "series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls |
| Analysis |
metabolomica |
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metabolomics |
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systeembiologie |
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systems biology |
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bioinformatics |
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Metabolomics |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 20, 2015) |
| Subject |
Molecular biology -- Laboratory manuals
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Systems biology -- Laboratory manuals
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Metabolism.
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Tissue extracts.
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Biochemistry.
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Computational biology.
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Bioinformatics.
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Chemistry.
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Life sciences.
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Biology.
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Physical sciences.
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Methodology.
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Metabolism
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Publication Formats
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Investigative Techniques
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Tissue Extracts
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Biochemistry
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Computational Biology
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Phenomena and Processes
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Complex Mixtures
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Chemistry
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Biological Science Disciplines
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Biology
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Analytical, Diagnostic and Therapeutic Techniques and Equipment
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Publication Characteristics
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Natural Science Disciplines
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Chemicals and Drugs
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Disciplines and Occupations
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Metabolomics
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Laboratory Manuals
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Metabolome
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Methods
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Cell Extracts
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metabolism (biological concept)
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biochemistry.
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chemistry.
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biological sciences.
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biology.
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physical sciences.
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methodology.
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Life sciences: general issues.
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Molecular biology.
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Science -- Life Sciences -- General.
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Science -- Life Sciences -- Anatomy & Physiology.
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Tissue extracts
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Physical sciences
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Methodology
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Metabolism
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Life sciences
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Computational biology
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Chemistry
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Biology
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Bioinformatics
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Biochemistry
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Molecular biology
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Systems biology
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Bjerrum, Jacob T., editor.
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| ISBN |
9781493923779 |
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1493923773 |
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1493923765 |
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9781493923762 |
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