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Title Diabetes and cancer : epidemiological evidence and molecular links / volume editors, K. Masur, F. Thévenod, K.S. Zá̈nker
Published Basel ; New York : Karger, 2008


Description 1 online resource (pages .)
Series Frontiers in diabetes, 0251-5342 ; v. 19
Frontiers in diabetes ; v. 19. 0251-5342
Contents Pathophysiology of diabetes mellitus type 2 : roles of obesity, insulin resistance, and B-cell dysfunction / Thévenod, F -- In vivo B-cell imaging in diabetes, B-cell hyperplasia, and insulinoma -- / Otthardt, M., Béhé, M., Lasser, T. -- Incretin-based therapies for the treatment of type 2 diabetes -- DPP-4 inhibitors and incretin mimetics / Gallwitz, B. -- Janus face of glucose and glucose-regulating hormones / Masur, K. -- Role of glucose metabolism in carcinogenesis and cancer progression / Gatenby, R.A. -- Glucose transporters : their abnormalities and significance in type 2 diabetes and cancer / Schürmann, A. -- The epidemiologic relationship between diabetes and cancer / Zänker, K.S. -- Diabetes mellitus and breast cancer / Wolf, I., Rubinek, T. -- Nutrition, diabetes, and cancer / LaValle, J.B. -- Diabetes and cancer : the road ahead / Masur, K., Thévenod, F., Zänker, K.S
Summary The interdisciplinary work revealing varied roles in biological processes of chronic diseases has led to a new field of research concerning common molecular and clinical features of chronic diseases. Epidemiological literature suggests an association between the history of metabolic syndrome/diabetes mellitus type 2 and the risk of developing a variety of cancers. This book, at the forefront of experimental and clinical research, is the first to highlight the common molecular links between these two diseases. These tight links indicate a complex interdependency between both diseases on a cellular and hormonal basis, which is influenced by a variety of aspects (e.g. nutritional, social and neuro-immunological factors). Special attention has been given to the fundamental role of the switch from oxidative phosphorylation to glycolysis of cancer cells - the Warburg effect. Offering insights into the interdisciplinary approaches of tomorrow, this publication will encourage endocrinologists, oncologists, diabetologists, general practitioners, diabetic nurses and students of life sciences working separately on various aspects of diabetes and cancer to come together and combine therapies and strategies
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Diabetes -- Epidemiology
Diabetes -- Molecular aspects
Metabolic syndrome -- Complications
Cancer -- Etiology.
Diabetes Mellitus -- epidemiology
Diabetes Mellitus -- metabolism
Risk Factors
Metabolic Syndrome -- complications
Neoplasms -- etiology
Cancer -- Etiology
Diabetes -- Epidemiology
Diabetes -- Molecular aspects
Form Electronic book
Author Masur, K. (Kai)
Thévenod, F. (Frank)
Zänker, Kurt S.
S. Karger (Firm)
ISBN 9783805586412