| Description |
1 online resource (xvii, 721 pages) : illustrations |
| Series |
Methods in molecular medicine ; 67 |
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Methods in molecular medicine ; 67.
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| Contents |
Microbiology and laboratory diagnosis / K. Cartwright-Isolation, culture, and identification of meningococci from clinical specimens / P. Olcen and H. Fredlund-Pcr diagnosis / M. Guiver and R. Borrow-Detection of meningococcal antigen by latex agglutination / M.A. Sobanski, R.A. Barnes and W.T. Coakley-Meningococcal serology / S.J. Gray, R. Borrow and E.B. Kaczmarski-Antibiotic susceptibility testing / C. Block-Molecular approach for the study of penicillin resistance in neisseria meningitidis / L. Arreaza and J.A. Vazquez-Overview: Epidemiology, surveillance, and population biology / M.C. Maiden and N.T. Begg-Serological characterization / B. Kuipers [and others]-Pulsed-field gel electrophoresis / M. Achtman and G. Morelli-Nucleotide sequencing of antigen genes of neisseria meningitidis / R. Urwin-Multi-locus sequence typing / K.A. Jolley-Capsular operons / U. Vogel, H. Claus and M. Frosch-Molecular analysis of the meningococcal lps expression / M.P. Jennings, A.W. Berrington and E.R. Moxon-Genome sequencing and annotation / A.C. Jeffries, N.J. Saunders and D.W. Hood-Representational difference analysis / L.D. Bowler, A. Bart and A. van der Ende-Managing outbreaks : The public health response / J.M. Stuart-Global trends in meningococcal disease / D.A. Caugant-Epidemiology, surveillance, and population biology : Carriage studies / K. Cartwright-Surveillance of meningococcal disease in europe / N. Noah-Global surveillance for meningococcal disease / N.E. Rosenstein-Epidemiology of meningococcal disease in north america / A.J. Pollard, D. Scheifele and N. Rosenstein-Computational methods for meningococcal population studies / K.A. Jolley and R. Urwin-Clinical studies : An overview / F.A. Riordan and A.J. Pollard-Clinical scoring systems in meningococcal disease / M. Festa and B. Derkx-Quantitative detection of bacterial lipopolysaccharides in clinical specimens / P. Brandtzaeg, R. Ovstebo and P. Kierulf-Isolation and analysis of radiolabeled meningococcal endotoxin / P.C. Giardina [and others]-Cytokine measurement in vivo and in vitro / M. van Deuren and P. Brandtzaeg-Cytokine bioassays / N.B. Liabakk [and others]-Molecular analysis of gene-polymorphisms affecting the host response to infection / R.G. Westendorp and T.W. Huizinga-Coagulation studies / J.A. Hazelzet, C.E. Hack and R. de Groot-Complement pathways and meningococcal disease : Diagnostic aspects / A.G. Sjoholm, L. Truedsson and J.C. Jensenius-Evaluation of new treatments for meningococcal disease / S. Nadel, I. Macintosh and M. Levin-Studies on the effect of neisserial porins on apoptosis of mammalian cells / P. Massari and L.M. Wetzler-Molecular recognition mechanisms of meningococci : Identifying receptor-ligand pairs involved in microbe-host interactions / M. Virji and L. Serino-Experimental nasopharyngeal colonization by neisseria meningitidis using explant organ culture / R.C. Read and L. Goodwin-Invasion of the central nervous system by neisseria meningitidis / C. Tinsley and X. Nassif-Interactions of meningococci with endothelium / R.S. Heyderman and N.J. Klein-A promoter probe plasmid based on green fluorescent protein : A strategy for studying meningococcal gene expression / S.A. Webb, P.R. Langford and J.S. Kroll-Signature-tagged mutagenesis / S. Bakshi [and others] |
| Summary |
Neisseria meningitidis is a major cause of childhood morbidity and mortality in industrialized nations and is responsible for epidemics of meningococcal meningitis and septic shock in Africa and Asia. In Meningococcal Disease: Methods and Protocols, Andrew Pollard and Martin Maiden bring together a panel of leading authorities to produce a comprehensive, interdisciplinary survey of recent advances and knowledge about this much-feared disease. The review and methods-based chapters collected here provide essential information for diagnosis in the clinical microbiology laboratory, isolate characterization, clinical management, and control of meningococcal disease. They also examine the immunopathological mechanisms occurring in the acutely ill, host-pathogen interactions, and the possible components of meningococcus responsible for virulence. A companion volume, Meningococcal Vaccines, provides detailed methods for the design and evaluation of meningococcal vaccines. Comprehensive and authoritative, Meningococcal Disease: Methods and Protocols integrates the basic science and the clinical and epidemiological aspects of this terrible infectious disease to promote the deeper understanding needed to identify novel targets for therapeutic interventions and vaccines |
| Notes |
Source of title; title from title screen |
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Companion volume to: Menngococcal vaccines |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| In |
Springer Protocols |
| Subject |
Neisseria meningitidis -- Laboratory manuals
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Meningitis -- Molecular aspects -- Laboratory manuals
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Meningitis, Meningococcal -- diagnosis
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Meningitis, Meningococcal -- therapy
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HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
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MEDICAL -- Neurology.
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Neisseria meningitidis
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Meningokokken.
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Wetenschappelijke technieken.
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Pollard, Andrew J.
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Maiden, Martin C. J.
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| ISBN |
9781592591497 |
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1592591493 |
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0896038491 |
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9780896038493 |
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