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Title Handbook of meningococcal disease : infection biology, vaccination, clinical management / edited by Matthias Frosch, Martin C.J. Maiden
Published Weinheim : Wiley-VCH ; Chichester : John Wiley distributor, [2006]


Location Call no. Vol. Availability
Description xlvii, 544 pages : illustrations (some color) ; 25 cm
Contents Historical aspects / Keith Cartwright -- The population biology of Neisseria meningitidis : implications for meningococcal disease, epidemiology and control / Martin C.J. Maiden and Dominique A. Caugant -- Methods for typing of meningococci / Keith A. Jolley [and others] -- Antibiotic resistance / Colin Block and Julio A. Vázquez -- Neisseria meningitidis genome sequencing projects -- Phase variation and adaptive strategies of N. meningitidis : insights into the biology of a commensal and pathogen / Peter M. Power and Richard Maxon -- Meningococcal transformation and DNA repair / Tonje Davidsen, Ole Herman Ambur and Tone Tønjum -- Structure and genetics of the meningococcal capsule / Matthias Frosch and Ulrich Vogel -- Genetics, structure and function of lipopolysaccharide / J. Claire Wright, Joyce S. Plested and E. Richard Moxon -- Major outer membrane proteins of meningococci / Jeremy Derrick, John E. Heckels and Mumtax Virji -- Iron metabolism in Neisseria meningitidis / Andrew Ekins and Anthony B. Schryvers -- Genetics, structure and function of pili / Philippe C. Morand and Thomas Rudel -- Mechanisms of attachment and invasion / Sandrine Bourdoulous and Xavier Nassif -- Role of complement in defense against meningococcal infection / Sanjay Ram and Ulrich Vogel -- Cellular immune responses in meningococcal disease / Oliver Kurzai and Matthias Frosch -- Surrogates of protection / Ray Borrow and Elizabeth Miller -- Conjugate vaccines / Neil Ravenscoft and Ian M. Feavers -- Outer membrane vesicle-based meningococcal vaccines / Jan T. Poolman [and others] -- Genome mining and reverse vaccinology / Rosanna Leuzzi [and others] -- Vaccination for the control of the meningococcal disease : the use of meningococcal vaccines of the public health perspective / Elisabeth Miller, Mary Ramsay and Helen Campbell -- Pathogenesis and pathophysiology of invasive meningococcal disease / Petter Brandtzaeg -- Course of disease and clinical management / Andrew J. Pollard and Simon Nadel -- Public health management / James Stuart
Summary A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. This volume uniquely summarizes the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function.
Bibliography Includes bibliographical references and index
Subject Meningitis.
Neisseria meningitidis.
Author Frosch, Matthias.
Maiden, Martin C. J.
ISBN 3527312609
9783527312603 :