| Description |
1 online resource (xx, 347 pages) : illustrations |
| Contents |
High resolution structures of membrane proteins: from X-ray crystallography to an integrated approach of membranes / Eva Pebay-Peyroula -- Membrane protein structure determination by electron cryo-microscopy / Christopher G. Tate and John L. Rubinstein -- Introduction to solid-state NMR and its application to membrane protein-ligand binding studies / Krisztina Varga and Anthony Watts -- Analytical ultracentrifugation: membrane protein assemblies in the presence of detergent / Christine Ebel, Jesper V. Møller and Mard le Mairie -- Probing membrane protein interactions with real-time biosensor technology / Iva Navratilova, David G. Myszka and Rebecca L. Rich -- Atomic force microscopy: high-resolution imaging of structure and assembly of membrane proteins / Simon Scheuring [and others] -- Molecular dynamics studies of membrane proteins: outer membrane proteins and transporters / Syma Khalid, John Holyoake and Mark S.P. Sansom -- Understanding structure and function of membrane proteins using free energy calculations / Christophe Chipot and Klaus Schulten -- Neutrons to study the structure and dynamics of membrane proteins / Kathleen Wood and Giuseppe Zaccai -- Circular dichroism: folding and conformational changes of membrane proteins / Nadege Jamin and Jean-Jacques Lacapere -- Membrane protein structure and conformational change probed using fourier transform infrared spectroscopy / John E. Baenziger and Corrie J.B. daCosta -- Resonance Raman spectroscopy of light-harvesting protein / Andrew Aaron Pascal and Bruno Robert -- Energy transfer technologies to monitor the dynamics and signaling properties of g-protein-coupled receptors in living cells / Jean-Philippe Pin [and others] |
| Summary |
Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new insights. Following an introduction, further sections discuss structural approaches, molecular interaction and large assemblies, dynamics and spectroscopies, finishing off with an exploration of structure-function relationships in whol |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Cell membranes -- Physiology.
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Membrane proteins -- Analysis.
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Membrane proteins -- Structure-activity relationships.
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Physical biochemistry.
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Biophysics -- methods.
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Membrane Proteins -- chemistry.
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Membrane Proteins -- physiology.
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| Form |
Electronic book
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| Author |
Pebay-Peyroula, Eva.
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| ISBN |
1282784218 |
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3527621237 (electronic bk.) |
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9781282784215 |
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9783527621231 (electronic bk.) |
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(alk. paper) |
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(alk. paper) |
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