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Book Cover
E-book
Author Willis, A. L., author

Title CRC Handbook of Eicosanoids, Volume II : Prostaglandins and Related Lipids
Published Boca Raton : CRC Press LLC July 2017 Florence : Taylor & Francis Group [distributor]

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Description 1 online resource (416 pages)
Series CRC Press Revivals Ser
CRC Press Revivals Ser
Contents 1. Introcution to the area 2.Therapeutic Promise of the Eicosanoid Area: An Overview 3. Inhibitors of Eicosanoid production 4. Antiphospholipase Proteins: Introduction and Overview 5. Effects of Corticosteroids on Release of Eicosanoid Precursors 6. Drugs that Inhibit the Activities or Activation of Phospholipases and Other Acylhydrolases 7. Cyclooxygenase Inhibitors 8. Lipoxygenase Inhibitors 9. Selective Inhibitors of Thromboxane Synthetase 10. Modulators of Eicosanoid actions 11. Classification of Prostanoid Receptors 12. Eicosanoid Receptor Antagonists 13. Leukotriene Antagonists 14. Regulation of Cyclic Nucleotide Metabolism in Human Platelets by Prostanoids 15. Opposite Effects of Prostaglandins on Human Platelets Mediated by Distinct Protein Kinases. Index
Summary Annotation Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This handbook will thus be invaluable for medicinal chemists, pharmacologists, and all those involved in basic research in the eicosanoid area. In addition, many parts of this handbook are suitable for use by university lecturers and students. There are 20 figures and 44 extensive tables as well as a bibliography containing more than 2,000 references that complement the text
Audience Scholarly & Professional CRC Press LLC
Subject Arachidonic acid -- Derivatives -- Handbooks, manuals, etc
Prostaglandins -- Handbooks, manuals, etc
Leukotrienes -- Handbooks, manuals, etc
SCIENCE / Chemistry / Organic.
MEDICAL / Pharmacology.
drug development.
eicosanoid research.
medicinal chemists.
pharmacologists.
biochemical data.
Arachidonic acid -- Derivatives.
Leukotrienes.
Prostaglandins.
Genre/Form Electronic book
Handbooks and manuals.
Form Electronic book
Author CRC Press LLC
ISBN 1138105066
9781138105065
Other Titles CRC Handbook of Eicosanoids, Volume II (Online)