An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES)
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS
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Map librarians. : Map librarianship : a guide to geoliteracy, map and GIS resources and services / Susan Elizabeth Ward Aber, Jeremy Ward Aber
--subdivision Map collections under names of individual persons, families, and corporate bodies
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Map Library (British Library) / http://id.loc.gov/authorities/names/n83170524 : Compassing the vaste globe of the earth : studies in the history of the Hakluyt Society, 1846-1996 : with a complete list of the Society's publications / edited by R.C. Bridges and P.E.H. Hair
Here are entered works on the general science of mapmaking, including map projection and the mapping of large areas. Works on the mapping of small areas and the drawing of maps in elementary schools are entered under Map drawing --subdivision Cartography under individual wars, e.g. World War, 1939-1945--Cartography
High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules
High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules
High molecular weight proteins found in the MICROTUBULES of the cytoskeletal system. Under certain conditions they are required for TUBULIN assembly into the microtubules and stabilize the assembled microtubules
Mapa Quinatzin. : In the palace of Nezahualcoyotl : painting manuscripts, writing the pre-Hispanic past in early colonial period Tetzcoco, Mexico / by Eduardo de J. Douglas
2010
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Mapa Tlohtzin. : In the palace of Nezahualcoyotl : painting manuscripts, writing the pre-Hispanic past in early colonial period Tetzcoco, Mexico / by Eduardo de J. Douglas
MAPHealth project : Safeguarding the health sector in times of macroeconomic instability : policy lessons for low- and middle-income countries / edited by Slim Haddad, Enis Baris, Delampady Narayana
