Title Eukaryome impact on human intestine homeostasis and mucosal immunology : overview of the first Eukaryome Congress at Insitut Pasteur. Paris, October 16-18 2019 / Nancy Guillen, editor

Published Cham : Springer, 2020

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Description 1 online resource (368 pages) Contents Intro -- Eukaryome Foreword -- Preface -- Contents -- 1 Eukaryome: Emerging Field with Profound Translational Potential -- Introduction -- The Diversity of Species Within the Human Intestinal Eukaryome -- Evolution of Microbial Eukaryotes in the Human Intestine -- Impact of Eukaryome Species in Human Populations -- Protozoan Feed on Bacteria from the Microbiome -- The Eukaryome, Public Health and Zoonosis -- Tissue Homeostasis and Immune-Modulatory Roles of the Eukaryome -- Cytokines as Major Players of Intestinal Immunity During Parasite Infection Tissue Protection Against Microbial Eukaryotes -- Intestinal Models to Study Eukaryome-Microbiome-Host Interplay -- References -- 2 Resolving Amoebozoan Encystation from Dictyostelium Evo-Devo and Amoebozoan Comparative Genomics -- Encystation as a Universal Protist Survival Strategy -- Insights into Encystation from Dictyostelium Sporulation -- References -- 3 Integrative Omics Analysis of the Effect of Bacteria on the Resistance of Entamoeba histolytica to Oxidative Stress -- Introduction E. coli Confers Resistance to OS to E. histolytica and Has an Effect on the Redox Proteome of the Parasite -- E. coli Has an Effect on the Transcriptome of E. histolytica Exposed to OS -- Integration of Redox Omics and Transcriptomics Data on the Response of E. histolytica to OS in Presence of E. coli -- Perspectives -- References -- 4 Histomonas meleagridis Molecular Traits-From Past to Future -- Introduction-Histomonas meleagridis and Histomonosis -- Defined in Vitro Cultures-An Essential Fundament for Molecular Research -- Histomonas meleagridis-Phylogenetic Positioning Histomonas meleagridis-Omics Studies -- Conclusions and Future Aspects -- References -- 5 Exploring the Biology and Evolution of Blastocystis and Its Role in the Microbiome -- General Introduction -- Prevalence, Diversity and Biogeography -- Blastocystis and Microbiome -- Blastocystis Biology -- Blastocystis MROs -- Conclusion -- References -- 6 Advances in the Study of Blastocystis spp. in Mexico: Prevalence, Genetic Diversity, Clinical Association and Their Possible Role in the Human Intestine -- Background -- Advances in the Study of Blastocystis spp. in Mexico Genetic Diversity and Geographical Distribution of Blastocystis Subtypes -- Clinical Association or Commensal Behavior of Blastocystis spp. -- Interaction of Blastocystis spp. and the Gut Microbiota of Asymptomatic Individuals -- Blastocystis spp. and Their Effect on the Immune Response -- References -- 7 Cryptosporidium Infection in Bangladesh Children -- Introduction -- Genomic Diversity in Bangladesh Cryptosporidium hominis -- Polymorphic DNA -- Recombination -- Conclusions -- References Summary The intestine is home to diverse bacterial communities forming the microbiome that influences host nutrition, immune functions and health. DNA-based methods have been instrumental to gain insight into the microbial eukaryotic diversity of the human gut. For instance, the microbiome share the intestinal ecosystem with a population of uni- and multi-cellular eukaryotic organisms. These eukaryotic organisms are very common and often very abundant in individuals with intestinal healthy conditions as well as those with intestinal diseases. The impact of the relationship between bacterial and eukaryotic organisms within the intestinal ecosystem on homeostasis and intestinal diseases is limited and can be considered an important emerging field of research. In addition, the factors that differentiate pathogenic eukaryotes from commensals are still unknown. Our interest focuses on the families of eukaryotic microbes inhabiting the intestine, called "intestinal eukaryome", that include fungi, protists and helminths. All these organisms and their interplay with bacteria and the human immune system are a challenge to assess the impact (present and future) of intestinal infectious diseases on public health. This book presents an overview of the science presented and discussed in the First Eukaryome Congress, held from October 16th to 18th, 2019 at Pasteur Institute in Paris, France. This contributed volume is of special interest for PhD students, postdoctoral fellows, researchers and clinicians interested in the effect of the eukaryotic microbiome on human health Notes 8 The Current Molecular Epidemiological Scenario of Cryptosporidium, Giardia and Blastocystis in Spain. Implication for Public Health Bibliography Includes bibliographical references Notes Print version record Subject Eukaryotic cells -- Congresses Intestines -- Microbiology. Homeostasis. Gastrointestinal Microbiome Eukaryotic Cells -- microbiology Host Microbial Interactions Homeostasis Medical parasitology. Microbiology (non-medical) Medical research. Medical microbiology & virology. Medical -- Parasitology. Science -- Life Sciences -- Biology -- Microbiology. Science -- Life Sciences -- Biology -- Molecular Biology. Medical -- Microbiology. Intestines -- Microbiology Homeostasis Eukaryotic cells Protists. Cèl·lules eucariotes. Malalties intestinals. Genre/Form proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. Llibres electrònics. Form Electronic book Author Guillen, Nancy ISBN 9783030448264 3030448266 3030448258 9783030448257

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