Title Late effects of cancer treatment on normal tissues : CURED I, LENT / P. Rubin [and others] (eds.) ; with contributions by M.J. Adams [and others] ; foreword by L.W. Brady [and others]

Published Berlin ; New York : Springer, ©2008

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Description 1 online resource (xxii, 140 pages) : illustrations, portraits Series Medical radiology, 0942-5373 Medical radiology. 0942-5373 Contents Radiation (and Medical) Biosurveillance -- Medical Countermeasures to Radiation Injury -- Ionizing Radiation and the Endothelium -- Inflammation and Cell Adhesion Molecules are Involved in Radiation-Induced Lung Injury -- Volume Effects in Radiation Damage to Rat Lung -- The Role of Imaging in the Study of Radiation-Induced Normal Tissue Injury -- Screening for Cardiovascular Disease in Survivors of Thoracic Radiation -- Hypoxia-Mediated Chronic Normal Tissue Injury -- Prevention and Treatment of Radiation Injuries -- Second Malignancies as a Consequence of Radiation Therapy -- Using Quality of Life Information to Rationally -- Cancer-Related Fatigue as a Late Effect: -- Normal Tissue TNM Toxicity Taxonomy -- Cancer Survivorship Research Summary The search for the most favorable therapeutic ratio - at which ablation of cancer is achieved while normal tissues are conserved - has been modern radiation oncology's equivalent of the quest for the Holy Grail. Our awareness of the late effects of radiation grew during the past century as new modalities were introduced. Heightened normal tissue reactions accompanied the higher rates of cancer ablation achieved by escalation of radiation doses, accelerated fractionated radiotherapy, and aggressive concurrent chemotherapy and radiation regimens. This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. Written by experts in the field, it addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that it will assist the reader in understanding how to prevent and treat the long-term side-effects of irradiation Bibliography Includes bibliographical references and index Notes English Print version record Subject Cancer -- Radiotherapy -- Complications -- Congresses Radiotherapy -- Side effects -- Congresses Radiation injuries -- Congresses Radiotherapy -- Complications. Radiation injuries. Cancer -- Radiotherapy -- Complications. Radiotherapy. Neoplasms -- radiotherapy Radiotherapy -- adverse effects Radiation Injuries Radiotherapy Dosage Radiotherapy MEDICAL -- Oncology. HEALTH & FITNESS -- Diseases -- Cancer. Radiation injuries. Neoplasms -- Radiotherapy. Radiotherapy -- adverse effects. Radiotherapy Dosage. Cancer -- Radiothérapie -- Complications et séquelles. Radiothérapie. Mal des rayons. Cancer -- Radiotherapy -- Complications. Radiotherapy -- Side effects. Radiotherapy -- Complications Radiotherapy Cancer -- Radiotherapy -- Complications Radiation injuries Genre/Form proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. Form Electronic book Author Rubin, Philip, 1927- LC no. 2006940402 ISBN 9783540490692 3540490698 9783540490708 3540490701 9786611148317 6611148310 1281148318 9781281148315

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