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Title Protozoans in macrophages / [edited by] Eric Y. Denkers, Ricardo T. Gazzinelli
Published Austin, Tex. : Landes Bioscience, ©2007


Description 1 online resource (1 volume)
Series Medical intelligence unit
Medical intelligence unit (Unnumbered : 2003)
Contents Invasion and intracellular survival by Toxoplasma / L. David Sibley [and others] -- Macrophages, alternative niches for intracellular growth of Trypanosoma cruzi / Julio Scharfstein and Marcos Andre Vannier dos Santos -- Macrophage-leishmania interactions : complexities and uncertainties from the study of leishmaniasis in vivo / Paul M. Kaye -- Innate recognition, cell signaling and pro-inflammatory response during infection with Trypanosoma cruzi / Catherine Ropert and Ricardo T. Gazzinelli -- Modulation of positive signaling and proinflammatory responses by hemozoin, a plasmodium metabolic waste / Martin Olivier and Maritza Jaramillo -- Pro-inflammatory responses and cell signaling during malaria infection : the parasite glycosylphosphatidylinositol ligand / D. Channe Gowda -- Pro-inflammatory responses in macrophages during Toxoplasma gondii infection / Katherine S. Masek and Christopher A. Hunter -- Down-modulation of proinflammatory signal transduction in Toxoplasma gondii-infected macrophages / Barbara A. Butcher [and others]
Avoidance of innate immune mechanisms by the protozoan parasite, Leishmania spp / David M. Mosser and Suzanne A. Miles -- Survival strategies of Toxoplasma gondii : interference with regulatory and effector functions of macrophages / Carsten G.K. Luder -- Targeting SHP-1 to prevent macrophage activation promotes leishmania pathogenesis / Devki Nandan and Neil E. Reiner -- Negative signaling and modulation of macrophage function in Trypanosoma cruzi infection / Flavia L. Ribeiro-Gomes, Marcela F. Lopes and George A. DosReis -- Effector functions of macrophages in plasmodium parasite infections / Mariela Segura [and others] -- Innate control of Toxoplasma gondii through macrophage-based effector mechanisms / Gregory A. Taylor -- Phagocyte effector functions against leishmania parasites / Christian Bogdan -- Effector mechanisms of macrophages infected with Trypanosoma cruzi / Fredy R.S. Gutierrez
Summary Using as a theme the encounter between protozoan parasites and macrophages, this volume brings together cell biologists, immunologists and protozoologists to review current developments in this broad and dynamic research area. Discussed are ways protozoans establish their intracellular niche, how they activate macrophage effector functions, what these functions are, and means by which several protozoans subvert macrophage activity. What emerges is a picture of the macrophage as a key cell type in the host response to protozoan infection. How these cells respond, and how their responses can be
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Protozoa, Pathogenic.
Macrophages -- parasitology
Protozoa -- pathogenicity
Immune System -- physiopathology
Protozoan Infections -- immunology
MEDICAL -- Infectious Diseases.
HEALTH & FITNESS -- Diseases -- Contagious.
Protozoa, Pathogenic
Form Electronic book
Author Denkers, Eric Y.
Gazzinelli, Ricardo T.
ISBN 9781435602380