Limit search to available items
Book Cover

Title MIF : most interesting factor / editor, Richard Bucala
Published Singapore ; New Jersey : World Scientific, ©2007
Online access available from:
World Scientific    View Resource Record  


Description 1 online resource
Contents Historical overview / R. David -- MIF "rediscovered" / R. Bucala -- Immunopathologic mechanisms relevant to diseases / H.Y. Lan -- Structural studies of MIF / E. Lolis -- MIF redox activity / J. Bernhgaen -- MIF receptor-mediated signal transduction / C. Leng -- MIF in innate immunity and infectious diseases / T. Calandra -- MIF in parasitic and helminth infections / A.R. Satoskar -- MIF in the pathogenesis of kidney disease / R.C. Atkins -- MIF and CNS autoimmune disease / T.G. Forsthuber -- MIF: wound repair / G.S. Ashcroft -- MIF and atherosclerosis / C. Weber -- Inflammatory arthritis / E. Morand -- MIF alleles in infammatory arthritis / R. Donn -- Adhesion-dependent signaling and growth control / R. Mitchell
Summary In recent years, researchers have identified a pivotal, upstream role for macrophage migration inhibitory factor (MIF) in the innate immune response. This pioneering book describes this renaissance of knowledge in the biology of MIF. Topics covered include MIF's molecular mechanism of action, its counterregulatory action on the immunosuppressive properties of glucocorticoids, its role in the production of proinflammatory mediators as shown in cell-based and animal studies; and its central role in human inflammation. Human genetic studies have identified allelic forms of the MIF gene, and high-
Bibliography Includes bibliographical references and index
Subject Macrophage migration inhibitory factor.
Macrophage Migration-Inhibitory Factors
MEDICAL -- Immunology.
Macrophage migration inhibitory factor.
Form Electronic book
Author Bucala, Richard
ISBN 9812775919