Title Hematologic malignancies : methods and techniques / edited by Guy B. Faguet

Published Totowa, N.J. : Humana Press, ©2001

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Description 1 online resource (xv, 360 pages) : illustrations (some color) Series Methods in molecular medicine ; 55 Methods in molecular medicine ; 55. 1543-1894 Contents Cytogenetics analysis / A.A. Sandberg and Z. Chen -- FISH analysis / A.A. Sandberg and Z. Chen -- Comparative genomic hybridization for the analysis of leukemias and lymphomas / M. Baudis and M. Bentz -- Spectral karyotyping (SKY) of hematologic malignancies / E. Hilgenfeld [and others] -- Molecular genetic methods in diagnosis and treatment / P. Ward and A. Kinniburgh -- Detecting monoclonal immunoglobulin and T-cell receptor gene rearrangements in B- and T-cell malignancies by polymerase chain reaction / P.J. Sykes -- Quantifying residual leukemia by "clone-specific" polymerase chain reaction / M.J. Brisco -- NPM-ALK reverse transcriptase-polymerase chain reaction for detecting the t(2;5) of non-Hodgkin's lymphoma / S.A. Shurtleff, J.R. Downing and S.W. Morris -- Diagnostic flow cytometry in hematologic malignancies / G.E. Marti, M. Stetler-Stevenson and T. Fleisher -- Flow cytometric analysis of hematologic neoplasia / R.C. Braylan and J.B. Anderson -- In situ hybridization in flow cytometry / V.L. Mosiman and C.L. Goolsby -- Quantitative fluorescence cytometry / R.F. Vogt [and others] -- Methods in leukocyte cytochemistry / M.G. Hanly -- Immunohistochemistry in leukemias and lymphomas / M. Jaramillo, C. Rangel and T. Grogan -- Apoptosis / V. Chiarugi [and others] -- Cytokine receptors / H. Zola Summary Recent advances in molecular biology are transforming the treatment of hematologic malignancies by providing powerful new tools useful in both diagnosis and the assessment of new therapies. In Hematologic Malignancies: Methods and Techniques, a panel of acknowledged experts review many of the key molecular methods used for the diagnosis and subsequent management of hematologic malignancies. These clinically relevant techniques range from routine test procedures to highly sophisticated methods currently offered only by specialized reference laboratories, and fall into five major groups: cytogenetics, polymerase chain reaction, flow cytometry, cytochemistry and immunochemistry, and apoptosis and cytokine receptors. Presented by investigators with extensive experience, and serving not only as a reference for seasoned research and clinical laboratory personnel, but also as a guide for the less experienced, each method contains sufficient detail to ensure its successful replication. Serving both clinical and experimental needs, Hematologic Malignancies: Methods and Techniques provides an array of powerful tools that will guide clinicians- especially hematologists, oncologists, and pathologists-to better diagnose and manage their patients with hematologic malignancies, and enable researchers to assess the anticancer effect of agents that impact cancer cells at the molecular level Bibliography Includes bibliographical references and index Notes English Print version record In Springer Protocols Subject Lymphoproliferative disorders -- Research -- Methodology Pathology, Molecular -- Methodology Pathology, Cellular -- Methodology Human cytogenetics -- Methodology Polymerase chain reaction -- Methodology Flow cytometry -- Methodology Lymphomas. Cytology -- Technique. Histology -- Technique. Leukemia. Lymphoma Cytological Techniques Hematologic Neoplasms Histological Techniques Leukemia Polymerase Chain Reaction -- methods MEDICAL -- Oncology. HEALTH & FITNESS -- Diseases -- Cancer. Lymphomas Leukemia Histology -- Technique Cytology -- Technique Flow cytometry -- Methodology Polymerase chain reaction -- Methodology Wetenschappelijke technieken. Genre/Form Laboratory manuals. Manuels de laboratoire. Form Electronic book Author Faguet, Guy B. ISBN 0896035433 9780896035430 9781592590742 1592590748 1280820640 9781280820649 9786610820641 6610820643

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