Title Lymphocyte signal transduction / edited by Constantine Tsoukas

Published New York : Springer, ©2006

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Description 1 online resource (xvii, 302 pages) : illustrations Series Advances in experimental medicine and biology, 0065-2598 ; v. 584 Advances in experimental medicine and biology ; v. 584. 0065-2598 Contents Protein kinase C-theta (PKC[theta]): new perspectives on its functions in T-cell biology / Rina Barouch-Bentov and Amnon Altman -- Travel informations on the tec kinases during lymphocyte activation / Fabien Garc̦on and Jacques A. Nunès -- Inducible T-cell tyrosine kinase (ITK): structural requirements and actin polymerization / Constantine D. Tsoukas [and others] -- Differential requirements of PI3K subunits for BCR or BCR/CD19-induced ERK activation / Elena Vigorito and Martin Turner -- Protein tyrosine phosphatases in human disease / Tomas Mustelin -- The T-cell-specific adapter protein functions as a regulator of peripheral but not central immunological tolerance / Philip E. Lapinski [and others] -- Proximal signals controlling B-cell antigen receptor (BCR) mediated NF-[kappa]B activation / Miguel E. Moreno-García [and others] -- The adapter 3BP2: how it plugs into leukocyte signaling / Marcel Deckert and Robert Rottapel -- CTLA-4 regulation of T-cell function via RAP-1-mediated adhesion / Helga Schneider [and others] -- Protein crosstalk in lipid rafts / Raquel J. Nunes, Mónica A.A. Castro, and Alexandre M. Carmo -- Role of lipid rafts in activation-induced cell death: the fas pathway in aging / Anis Larbi [and others] -- T-cell response in aging: influence of cellular cholesterol modulation / Tamàs Fülöp [and others] -- Lymphocyte signaling and the translatability of mRNA / Suzanne Miyamoto -- Protein arginine methylation: a new frontier in T-cell signal transduction / Brandon T. Schurter, Fabien Blanchet, and Oreste Acuto -- Immune regulation by ubiquitin conjugation / K. Venuprasad [and others] CTIB (C-terminus protein of I[kappa]B-[beta]): a novel factor required for acidic adaptation /Toshiko Fukamachi [and others] -- HIV may deplete most CD4 lymphocytes by a mechanism involving signaling through its receptors on non-permissive resting lymphocytes / Miles W. Cloyd [and others] -- Integrating traditional and postgenomic approaches to investigate lymphocyte development and function / Yina Hsing Huang [and others] -- Phosphoproteomic analysis of lymphocyte signaling / Lulu Cao, Kebing Yu, and Arthur R. Salomon Summary Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference Analysis immunologie immunology infectieziekten infectious diseases microbiologie microbiology biomedische wetenschappen biomedicine Medicine (General) Geneeskunde (algemeen) Notes "Proceedings of the 3rd Lymphocyte Signal Transduction Conference, held May 27-June 1, 2005 in Crete, Greece"--Title page verso Bibliography Includes bibliographical references and indexes Notes Print version record Subject Lymphocytes -- Congresses Leucocytes -- Receptors -- Congresses Cellular signal transduction -- Congresses Post-translational modification -- Congresses Signal Transduction -- physiology -- Congresses Lymphocytes -- cytology Signal Transduction -- physiology MEDICAL -- Immunology. Leucocytes -- Receptors. Cellular signal transduction. Post-translational modification. Signal Transduction -- physiology. Lymphocytes. Leucocytes -- Récepteurs. Transduction du signal cellulaire. Protéines -- Modification post-traductionnelle. Lymphocytes -- cytology. Biomédecine. Sciences de la vie. Cellular signal transduction Lymphocytes Post-translational modification Genre/Form proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. Form Electronic book Author Tsoukas, Constantine ISBN 9780387341323 0387341323 0387313354 9780387313351 9786610743810 6610743819

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