| Description |
1 online resource (xiv, 309 pages) : illustrations |
| Series |
Cancer treatment and research ; 255 |
|
Cancer treatment and research ; 255
|
| Contents |
Landmarks and advances in translational lymphology / Marlys H. Witte, Kimberly Jones, Michael Bernas, and Charles L. Witte -- Embryonic development of the lymphovascular system and tumor lymphangiogenesis / Jörg Wilting, Maria Papoutsi, Kerstin Buttler, and Jürgen Becker -- Lymphatic origin from embryonic stem cells / Michael Dictor, Sofia Mebrahtu, Manuel Selg, Zerina Lokmic, and Lydia Sorokin -- Lymphatic markers, tumour lymphangiogenesis and lymph node metastasis / David G. Jackson -- Anatomy of the human lymphatic system / Mauro Andrade and Alfredo Jacomo -- SPECT-CT fusion imaging radionuclide lymphoscintigraphy : potential for limb lymphedema assessment and sentinel node detection in breast cancer / A.P. Pecking, M. Wartski, R.V. Cluzan, D. Bellet, and J.L. Albérini -- Sentinel node identification using radionuclides in melanoma and breast cancer / Edwin C. Glass -- Targeted introduction of substances into the lymph nodes for endolymphatic therapy / Peter Hirnle -- Mechanisms of metastasis : seed and soil / Adriano Piris and Martin C. Mihm, Jr. -- Preclinical models of regional lymph node tumor metastasis / S. David Nathanson -- A new breast cancer model for lymphatic metastasis / Michael M. Lizardo, Ian C. Macdonald, Alan B. Tuck, and Ann F. Chambers -- Lymph node micrometastases in lung cancer / Katharina E. Effenberger, Wulf Sienel, and Klaus Pantel -- Effects of chemokines on tumor metastasis / Hiroya Takeuchi, Minoru Kitago, and Dave S.B. Hoon -- Regional lymph node metastases, a singular manifestation of the process of clinical metastases in cancer : contemporary animal research and clinical reports suggest unifying concepts / Blake Cady -- Patterns of metastatsis in head and neck cancer / Jochen A. Werner -- Patterns of metastasis in human solid cancers / Stanley P.L. Leong, Blake Cady, David M. Jablons, Julio Garcia-Aguilar, Douglas Reintgen, J.A. Werner, and Yuko Kitagawa -- Significance of regional draining lymph nodes in the development of tumor immunity : implications for cancer immunotherapy / Rongxiu Zheng, Jorgen Kjaergaard, Walter T. Lee, Peter A. Cohen, and Suyu Shu -- Targeting small molecules in cancer / Harold J. Wanebo, David Berz, and Anthony Mega -- Update on the role of EGFR inhibitors in cancer therapeutics / Michalis V. Karamouzis and Athanassios Argiris -- New promises in the adjuvant, and palliative treatment of melanoma / Axel Hauschild, Dirk Schadendorf, Claus Garbe, Selma Ugurel, and Katharina C. Kähler -- Future perspectives and unanswered questions on cancer metastasis and the lymphovascular system / Stanley P.L. Leong and Marlys H. Witte |
| Summary |
Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of progression via the lymphatic network, while 20% of the time systemic metastasis occurs, bypassing the lymphatic system. During the past two decades, significant progress has been achieved in understanding the anatomical, functional, cellular and molecular aspects of the lymphovascular system and the metastasis process. · Molecular imaging advances help to localize early cancers more precisely. · Current status of the immune responses in the draining lymph nodes against cancer is summarized. · New paradigms of early cancer growth, proliferation, overcoming apoptosis are exploited in the development of anticancer treatment. In this book, basic scientists and clinicians exchange ideas so that laboratory findings can be applied to clinical dilemmas, and clinical problems can be targeted for research in the laboratory. Series editor's comments: "Cancer metastasis remains the greatest challenge for oncologists. The role of the lymphovascular system is critical and a focus of intense investigations. This text covers a spectrum of relevant research and clinical issues that impact on our understanding of this process." Steven T. Rosen, MD Series Editor |
| Analysis |
geneeskunde |
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medicine |
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volksgezondheid |
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public health |
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hematologie |
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haematology |
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oncologie |
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oncology |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Lymphatic metastasis.
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Lymphatic Metastasis -- physiopathology
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Neoplasm Metastasis -- physiopathology
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Lymphatic System -- physiology
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Neoplasms -- therapy
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Lymphatic Metastasis
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MEDICAL -- Oncology.
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HEALTH & FITNESS -- Diseases -- Cancer.
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Lymphatic Metastasis -- physiopathology.
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Neoplasm Metastasis -- physiopathology.
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Lymphatic System -- physiology.
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Neoplasms -- therapy.
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Lymphatic metastasis.
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Lymphatic metastasis
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| Form |
Electronic book
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| Author |
Leong, Stanley P. L.
|
| ISBN |
9780387692197 |
|
0387692193 |
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