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Title Clinical epidemiology of chronic liver diseases / Robert J. Wong, Robert G. Gish, editors
Published Cham, Switzerland : Springer, 2018

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Description 1 online resource (349 pages)
Contents Intro; Preface; Contents; 1: Principles of Clinical Epidemiology; 1.1 Defining a Population for Clinical Epidemiology Studies; 1.2 Defining Exposure; 1.3 Defining Outcome; 1.4 Descriptive Epidemiology; 1.5 Analytic Epidemiology; 1.6 Measures of Association; 1.7 Some Notes About Statistical Inference (p-Values and Confidence Intervals); 1.8 Bias; 1.8.1 Confounding; 1.8.2 Selection Bias; 1.8.3 Misclassification; 1.9 Generalizability; References; 2: Understanding Study Design for Clinical Epidemiology Studies; 2.1 Overview of Chapter; 2.2 Case Control Study; 2.2.1 Overview
2.3 Randomized Controlled Trial2.3.1 Overview; 2.4 Cohort Study; 2.4.1 Overview; References; 3: Understanding the Interpretation of Disease Incidence and Prevalence; 3.1 Frequency Data; 3.2 Incidence; 3.2.1 Cumulative Incidence (Incidence Proportion); 3.2.2 Incidence Density (Incidence Rate); 3.2.3 Incidence Odds; 3.3 Prevalence; 3.3.1 Point Prevalence; 3.3.2 Period Prevalence; 3.3.3 Prevalence Odds; 3.4 The Relationship Between Incidence and Prevalence; 3.5 Reporting Incidence and Prevalence; References; 4: Understanding Survival Analyses; 4.1 Introduction
4.1.1 What is Survival Analysis?4.1.2 Why Measure Survival Analysis?; 4.2 Basics and Definitions; 4.2.1 Censoring; 4.2.2 Distribution of Survival Data; 4.2.3 Survival Probability and Hazard Function; 4.2.4 Univariate Vs. Multivariate Models; 4.2.5 Collecting the Data; 4.3 Methods; 4.3.1 Kaplan-Meier Estimator; 4.3.2 Log-Rank Test; 4.3.3 Life Tables; 4.3.4 Cox Model; 4.3.5 Cox Model Assumptions; References; 5: Global Epidemiology of Chronic Liver Disease; 5.1 Introduction; 5.2 Chronic Liver Disease in Africa; 5.2.1 Epidemiology of Chronic HCV Infection in Africa
5.2.2 Epidemiology of Chronic HBV Infection in Africa5.2.3 Epidemiology of Alcoholic Liver Disease in Africa; 5.2.3.1 Epidemiology of Non-Alcoholic Fatty Liver Disease in Africa; 5.3 Epidemiology of Chronic Liver Disease in Asia; 5.3.1 Epidemiology of Chronic HBV and HCV in Asia; 5.3.2 Epidemiology of NAFLD in Asia; 5.4 Epidemiology of Chronic Liver Disease in Europe; 5.4.1 Epidemiology of Alcoholic Liver Disease in Europe; 5.4.2 Epidemiology of Chronic Hepatitis C in Europe; 5.4.3 Epidemiology of Chronic Hepatitis B in Europe; 5.4.4 Epidemiology of Hepatitis D Infection in Europe
5.4.5 Epidemiology of Hepatitis E Infection in Europe5.5 Epidemiology of Non-Alcoholic Fatty Liver Disease in Europe; 5.5.1 Genetic Disorders (Haemochromatosis, Alpha-1-Antitrypsin Deficiency & Wilson's Disease); 5.5.2 Autoimmune Hepatitis; 5.6 Chronic Liver Disease in Latin America; 5.6.1 Epidemiology of Chronic HBV Infection in Latin America; 5.6.2 Epidemiology of HCV Infection in Latin America; 5.7 Epidemiology of Non-Alcoholic Fatty Liver Disease in Latin America; Summary Table of Landmark Literature; References; 6: Epidemiology of Chronic Liver Disease in the United States
Summary This book emphasizes the clinical epidemiology of chronic liver diseases with a specific focus on the methodology of the discussed studies. The whole spectrum of liver diseases is covered, from chronic hepatitis B and C, to hepatocellular carcinoma, alcoholic and non-alcoholic fatty liver diseases and autoimmune and cholestatic liver diseases. Readers will find the most up-to-date information on clinical epidemiology of hepatology, and will also be able to learn about important methodology and biostatistics information. Each chapter contains a summary table at the end of each chapter that highlights the most relevant landmark studies, their main outcomes and the unique features of the methodology. The book will appeal to both practicing clinicians as well as clinical research investigators. In addition, this would likely be of interest to medical school or public health school students to learn about hepatology epidemiology, but also some specific fundamentals of clinical research and clinical epidemiology
Bibliography Includes bibliographical references
Notes 6.1 Introduction
Online resource; title from digital title page (viewed on July 08, 2019)
Subject Liver -- Diseases -- Epidemiology
Chronic diseases -- Epidemiology
Liver Diseases -- epidemiology
MEDICAL -- Forensic Medicine.
MEDICAL -- Preventive Medicine.
MEDICAL -- Public Health.
Chronic diseases -- Epidemiology
Form Electronic book
Author Wong, Robert J., editor
Gish, Robert G., editor
ISBN 9783319943558
3319943553