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Title Five-lipoxygenase products in asthma / edited by Jeffrey M. Drazen, Sven-Erik Dahlen, Tak H. Lee
Published New York : M. Dekker, [1998]
Online access available from:
ProQuest Ebook Central (owned titles)    View Resource Record  


Description 1 online resource (496 pages cm)
Series Lung biology in health and disease ; v. 120
Lung biology in health and disease ; v. 120
Contents Overview of the 5-Lipoxygenase Pathway / Jesper Z. Haeggstrom and Bengt Samuelson -- 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein / Jilly F. Evans -- Leukotriene C4 Synthase : A Pivotal Enzyme in the Biosynthesis of Cysteinyl Leukotrienes / John F. Penrose and K. Frank Austen -- Leukotriene A4 Hydrolase / Jesper Z. Haeggstrom -- Leukotriene Export in Human Leukocytes / Bing K. Lam -- Pathways of Leukotriene Metabolism in Isolated Cell Models and Human Subjects / Robert C. Murphy and Pat Wheelan -- Cell Biology of the 5-Lipoxygenase Pathway Amplification and Generation of Leukotrienes and Lipoxins by Transcellular Biosynthesis / Timothy D. Bigby, Bruce D. Levy, and Charles N. Serhan -- Leukotriene Receptors: Incompletely Defined Targets for Treatment of Asthma and Inflammation / Sven-Erik Dahlen -- Physiological Effects of the Leukotrienes in Humans / Neil C. Barnes and Lewis J. Smith -- Analysis of Leukotrienes and Lipoxins / Graham W. Taylor -- Measurement of Leukotrienes from Human Biological Fluids / Jay W. Westcott and Ian K. Taylor -- Cysteinyl-Leukotriene Receptor Antagonism and 5-Lipoxygenase Inhibition in Asthma / S.M. Shuaib Nasser and Tak H. Lee -- Leukotriene Receptor Antagonism and Synthesis Inhibition in Chronic Stable Asthma / Elliot Israel and Jeffrey M. Drazen -- Montelukast : An Antileukotriene Treatment for Asthma : Changing the Asthma-Treatment Paradigm / Beth C. Seidenberg and Theodore F. Reiss -- Pranlukast : The First Orally Active Cysteinyl Leukotriene Receptor Antagonist Marketed for the Treatment of Asthma / Jeffrey W. Dubb and Anthony S. Rebuck -- Zafirlukast / Catherine M. Bonuccelli and Trevor J.C. Higgins -- Zileuton : The First Leukotriene Synthesis Inhibitor for Use in the Management of Chronic Asthma / Louise M. Dube [and others] -- Antileukotrienes in the Management of Asthma / Paul M. O'Byrne
Summary This work offers an examination of the biochemistry, basic pharmacology and clinical pharmacology of the leukotrienes, with special emphasis on their role in asthma
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Asthma -- Chemotherapy.
Asthma -- Pathophysiology.
Leukotrienes -- Metabolism.
Leukotrienes -- Pathophysiology.
Lipoxygenase Inhibitors.
Arachidonate 5-Lipoxygenase -- metabolism.
Asthma -- drug therapy.
Leukotrienes -- metabolism.
Lipoxygenase Inhibitors -- therapeutic use.
Leukotriene Antagonists.
Form Electronic book
Author Dahlén, Sven-Erik.
Drazen, Jeffrey M., 1946-
Lee, T. H. (Tak Hong)
ISBN 0585270511 (electronic bk.)
0824746368 (electronic bk. ; Adobe Reader)
9780585270517 (electronic bk.)
9780824746360 (electronic bk. ; Adobe Reader)
Other Titles 5-lipoxygenase products in asthma