| Description |
1 online resource (496 pages cm) |
| Series |
Lung biology in health and disease ; v. 120 |
|
Lung biology in health and disease ; v. 120
|
| Contents |
Overview of the 5-Lipoxygenase Pathway / Jesper Z. Haeggstrom and Bengt Samuelson -- 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein / Jilly F. Evans -- Leukotriene C4 Synthase : A Pivotal Enzyme in the Biosynthesis of Cysteinyl Leukotrienes / John F. Penrose and K. Frank Austen -- Leukotriene A4 Hydrolase / Jesper Z. Haeggstrom -- Leukotriene Export in Human Leukocytes / Bing K. Lam -- Pathways of Leukotriene Metabolism in Isolated Cell Models and Human Subjects / Robert C. Murphy and Pat Wheelan -- Cell Biology of the 5-Lipoxygenase Pathway Amplification and Generation of Leukotrienes and Lipoxins by Transcellular Biosynthesis / Timothy D. Bigby, Bruce D. Levy, and Charles N. Serhan -- Leukotriene Receptors: Incompletely Defined Targets for Treatment of Asthma and Inflammation / Sven-Erik Dahlen -- Physiological Effects of the Leukotrienes in Humans / Neil C. Barnes and Lewis J. Smith -- Analysis of Leukotrienes and Lipoxins / Graham W. Taylor -- Measurement of Leukotrienes from Human Biological Fluids / Jay W. Westcott and Ian K. Taylor -- Cysteinyl-Leukotriene Receptor Antagonism and 5-Lipoxygenase Inhibition in Asthma / S.M. Shuaib Nasser and Tak H. Lee -- Leukotriene Receptor Antagonism and Synthesis Inhibition in Chronic Stable Asthma / Elliot Israel and Jeffrey M. Drazen -- Montelukast : An Antileukotriene Treatment for Asthma : Changing the Asthma-Treatment Paradigm / Beth C. Seidenberg and Theodore F. Reiss -- Pranlukast : The First Orally Active Cysteinyl Leukotriene Receptor Antagonist Marketed for the Treatment of Asthma / Jeffrey W. Dubb and Anthony S. Rebuck -- Zafirlukast / Catherine M. Bonuccelli and Trevor J.C. Higgins -- Zileuton : The First Leukotriene Synthesis Inhibitor for Use in the Management of Chronic Asthma / Louise M. Dube [and others] -- Antileukotrienes in the Management of Asthma / Paul M. O'Byrne |
| Summary |
This work offers an examination of the biochemistry, basic pharmacology and clinical pharmacology of the leukotrienes, with special emphasis on their role in asthma |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Asthma -- Chemotherapy.
|
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Asthma -- Pathophysiology.
|
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Leukotrienes -- Metabolism.
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Leukotrienes -- Pathophysiology.
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Lipoxygenase Inhibitors.
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Arachidonate 5-Lipoxygenase -- metabolism.
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Asthma -- drug therapy.
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Leukotrienes -- metabolism.
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Lipoxygenase Inhibitors -- therapeutic use.
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Leukotriene Antagonists.
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| Form |
Electronic book
|
| Author |
Dahlén, Sven-Erik.
|
|
Drazen, Jeffrey M., 1946-
|
|
Lee, T. H. (Tak Hong)
|
| ISBN |
0585270511 (electronic bk.) |
|
0824746368 (electronic bk. ; Adobe Reader) |
|
9780585270517 (electronic bk.) |
|
9780824746360 (electronic bk. ; Adobe Reader) |
|
