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Title The kinesin superfamily handbook : transporter, creator, destroyer / edited by Claire Friel
Edition First edition
Published Boca Raton : CRC Press, 2020
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Description 1 online resource (pages cm.)
Contents The kinesin superfamily / Hannah R. Belsham & Claire T. Friel -- The kinesin-1 family / David D. Hackney & Alison E. Twelvetrees -- The kinesin-2 family -- transporters / William O. Hancock -- The kinesin-3 family -- long distance cargo transporters / Nida Siddiqui & Anne Straube -- The kinesin-4 family / Claire T. Friel -- The kinesin-5 family : transporters and creators / Mary Popov, Alina Goldstein-Levitin & Larisa Gheber -- kinesin-6 / Claire T. Freil -- The kinesin-8 family / Tianyang Liu, Alejandro Pena, Fiona Shilliday & Carolyn A. Moores -- The kinesin-13 family -- specialist destroyers / Julie P. Welburn & Claire T. Friel -- The kinesin-14 family / Marcus Braun, Stefan Diez & Zdenek Lansky -- The kinesin-15 family / Hauke Drechsler, Jaspreet Singh Grewal & Andrew D. McAnish -- The kinesin-16 family / Hanan M. Alghamdi & Claire T. Freil -- Other kinesin Families / Claire T. Friel -- Summary and Future Perspectives / Claire T. Friel
Summary "This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for researchers looking to make comparisons between different families, for specific information on a family, or simply for an overview of the kinesin superfamily. Information is clearly structured and grouped according to individual families and organized in a standardized way, allowing the reader to search and retrieve information on this large superfamily of molecular motors and understand how its individual members carry out a diverse variety of cellular functions. Features: The first book dedicated to the entire kinesin superfamily Enables a fuller understanding of this family of proteins which is becoming an increasing focus of research due to its involvement in diseases such as cancer, neuropathies and ciliopathies. Written in a manner accessible to a range of researchers in the life and medical sciences, including biophysicists, biochemists, and medical researchers"--
Bibliography Includes bibliographical references and index
Notes Claire T. Friel earned a BSc in Biochemistry from the University of Glasgow, UK, and carried out her PhD work on protein folding kinetics in the laboratory of Sheena Radford at the University of Leeds, UK. In 2006, she joined the group of Jonathon Howard at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. There, she solved the ATP turnover cycle of the microtubule depolymerising Kinesin-13, MCAK, and developed an interest in the kinesin superfamily of molecular motors. Since 2011, Claire has held the position of Assistant Professor at the University of Nottingham, UK. The research goals of the Friel lab are to understand the relationship between the kinesin motor domain sequence and the many functional properties of the kinesin superfamily and to understand the molecular mechanisms of proteins that regulate microtubule dynamics
Description based on print version record
Subject Kinesin.
MEDICAL / Biochemistry
SCIENCE / Life Sciences / Cytology
SCIENCE / Physics
Form Electronic book
Author Friel, Claire (Claire T.), editor.
ISBN 0429491557
0429958234
0429958242
0429958250
9780429491559
9780429958236
9780429958243
9780429958250