Front Matter; The complement system in renal diseases; Complement in renal transplantation; C1q and the glomerulonephritides: therapeutic approaches for the treatment of complement-mediated kidney diseases; Complement deficient mice as model systems for kidney diseases; Non-Shiga toxin-associated hemolytic uremic syndrome; Role of complement and Factor H in hemolytic uremic syndrome; Genetic testing in atypical HUS and the role of membrane cofactor protein (MCP; CD46) and Factor I; Towards a new classification of hemolytic uremic syndrome
Summary
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. This book discusses Molecular biology, clinics and therapy
