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Book Cover
E-book
Author Laan, M. J. van der.

Title Targeted learning : causal inference for observational and experimental data / Mark J. van der Laan, Sherri Rose
Published New York : Springer, ©2011

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Description 1 online resource (xlix, 626 pages)
Series Springer series in statistics
Springer series in statistics.
Contents Models, Inference, and Truth -- The Open Problem -- Defining the Model and Parameter -- Super Learning -- Introduction to TMLE -- Understanding TMLE -- Why TMLE? -- Bounded Continuous Outcomes -- Direct Effects and Effect Among the Treated -- Marginal Structural Models -- Positivity -- Robust Analysis of RCTs Using Generalized Linear Models -- Targeted ANCOVA Estimator in RCTs -- Independent Case-Control Studies -- Why Match? Matched Case-Control Studies -- Nested Case-Control Risk Score Prediction -- Super Learning for Right-Censored Data -- RCTs with Time-to-Event Outcomes -- RCTs with Time-to-Event Outcomes and Effect Modification Parameters -- C-TMLE of an Additive Point Treatment Effect -- C-TMLE for Time-to-Event Outcomes -- Propensity-Score-Based Estimators and C-TMLE -- Targeted Methods for Biomarker Discovery -- Finding Quantitative Trait Loci Genes -- Case Study: Longitudinal HIV Cohort Data -- Probability of Success of an In Vitro Fertilization Program -- Individualized Antiretroviral Initiation Rules -- Cross-Validated Targeted Minimum-Loss-Based Estimation -- Targeted Bayesian Learning -- TMLE in Adaptive Group Sequential Covariate Adjusted RCTs -- Foundations of TMLE -- Introduction to R Code Implementation
Summary As the size of data sets grows ever larger, the need for valid statistical tools is greater than ever. This book introduces super learning and the targeted maximum likelihood estimator, and discusses complex data structures and related applied topics
Analysis statistiek
statistics
statistische analyse
statistical analysis
volksgezondheid
public health
geneeskunde
medicine
levenswetenschappen
life sciences
toegepaste statistiek
applied statistics
Statistics (General)
Statistiek (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Mathematical statistics.
Inference.
Inference.
Mathematical statistics.
Inferenzstatistik
Kausalität
Maschinelles Lernen
Datenanalyse
Genre/Form Electronic books
Form Electronic book
Author Rose, Sherri
LC no. 2011930854
ISBN 9781441997821
1441997822
9781441997814
1441997814