| Description |
1 online resource (359 pages) |
| Series |
Target organ toxicology series |
|
Target organ toxicology series.
|
| Contents |
Introduction: the gastrointestinal (GI) tract as a barrier and as an absorptive and metabolic organ / Shayne C. Gad -- Methods for the analysis of gastrointestinal function / Robin C. Guy -- Safety pharmacology and the GI tract / Henry I. Jacoby -- Gastronintestinal tract development and its importance in toxicology / Joseph V. Rodricks, Allison A. Yates, Claire L. Kruger -- The GI tract as the major route of pharmaceutical administration / Robert W. Kapp, Jr. -- Gastrointestinal function and toxicology in canines / Charles Spainhour -- Absorption of macromolecules by mammalian intestinal epithelium / Shayne C. Gad -- Peyer's patch epithelium: an imperfect barrier / Gary R. Burleson and Florence G. Burleson -- Alteration of intestinal function by xenobiotic exposure: animal models / Shayne C. Gad -- Intestinal absorption and metabolism of xenobiotics in laboratory animals / William J. Brock -- Normal and abnormal intestinal absorption by humans / David W. Hobson and Valerie L. Hobson -- Intestinal absorption and metabolism of xenobiotics in humans / William J. Brock |
| Summary |
This book replaces Intestinal Toxicology, one of the original books in the Target Organ series. It provides a complete, multidimensional overview of the entire gastrointestinal system involved in the toxicity of exogenous agents. The book describes normal structures and functions, regulatory mechanisms of control, and the role of absorption and metabolism in the systemic toxicity of toxic agents. It includes detailed treatment of the mechanisms of action of substances on the GI tract and how such effects can adversely affect the functioning of other systems in the body. The book also covers ph |
| Notes |
"A CRC title." |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Gastrointestinal system -- Pathophysiology
|
|
Toxicology.
|
|
Gastrointestinal Tract -- drug effects
|
|
Gastrointestinal Tract -- physiology
|
|
Intestinal Absorption -- drug effects
|
|
Toxicology
|
|
toxicology.
|
|
MEDICAL -- Gastroenterology.
|
|
Gastrointestinal system -- Pathophysiology
|
|
Toxicology
|
| Form |
Electronic book
|
| Author |
Gad, Shayne C., 1948-
|
| ISBN |
9781420004267 |
|
1420004263 |
|
