| Description |
1 online resource (568 pages) : text file, PDF |
| Contents |
Chapter 1 The Molecular Biology of Interferon-13 from Receptor Binding to Transmembrane Signaling / Lawrence M. Pfeffer -- chapter 2 The Molecular Biology of Type I Interferons (Interferon-a/13) (Gene Activation, Promoters, Proteins Induced) / Thomas Decker -- chapter 3 Pharmacokinetics of Interferon-fi and the Biological Markers It Induces / Patricia L. Witt -- chapter 4 Interferons and the Central Nervous System Glia / Timothy Vartanian -- chapter 5 Effects of Interferon on the Central Nervous System / Nachum Dafny -- chapter 6 Neuropsychological Effects of Interferon Therapy / Neil H. Pliskin -- chapter 7 The Effects of Interferon-a on Cytokines and Immune Responses / Peter Rieckmann -- chapter 8 The Pathogenetic Role of Interferon-y in Multiple Sclerosis / Gianvito Martino -- chapter 9 The Effects of Interferons and Other Cytokines on Experimental Autoimmune Encephalomyelitis / Hubertine Heremans -- chapter 10 Effects of Oral Administration of Type I Interferons on Experimental Autoimmune Encephalomyelitis / Staley A. Brod -- chapter 11 Interferon-a in the Treatment of Multiple Sclerosis / Lorne F. Kastrukoff and Joel J.-F. Oger -- chapter 12 Recombinant Interferon-a in the Treatment of Multiple Sclerosis: Effects on Exacerbation Rate, Magnetic Resonance Imaging of Lesion Activity, and Cytokines / Luca Durelli -- chapter 13 Interferon 3-1a Treatment of Multiple Sclerosis / Robert M. Herndon -- chapter 14 Interferon /3-lb (Betaseron) Treatment of Multiple Sclerosis / Robert L. Knobler -- chapter 15 Effects of Interferon /3-lb on Multiple Sclerosis Lesions Evaluated by Magnetic Resonance Imaging and Other Magnetic Resonance Techniques / Robert A. Koopmans -- chapter 16 Adverse Effects of Interferons / Richard Cirelli -- chapter 17 Interferon-r: A Potential Treatment for Inflammatory Central Nervous System Disease / Jeanne M. Soos -- chapter 18 Clinical Trials of Multiple Sclerosis / Jeremy C. Hobart -- chapter 19 The Incidence and Clinical Significance of Antibodies to Interferon-a / Kjell Oberg -- chapter 20 Quantitation and Characterization of Multiple Sclerosis Patient Antibodies to Interferon-fl / Eirik Nestaas, James G. Files, Jeffrey W. Nelson, and Erno Pungor, Jr |
| Summary |
This reference presents cutting-edge basic and clinical research on all forms of interferon (IFN) involvement in the management of multiple sclerosis (MS)-detailing topics from IFN-receptor molecular interactions to synergy and interference with other agents such as cytotoxic drugs and chemotherapy. Features detailed research findings on IFN ß -1a (Avonex) and IFN -1b (Betaseron) |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Interferon -- Therapeutic use
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Interferon.
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Interferonen
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Interferon -- pharmacology
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Multiple sclerosis -- Immunotherapy
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Multiple sclerosis -- Treatment
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MEDICAL -- Immunology.
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MEDICAL -- Anatomy.
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Multiple sclerosis -- Treatment
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Interferon
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Interferon -- Therapeutic use
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| Form |
Electronic book
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| Author |
Reder, Anthony T., 1952- editor.
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| ISBN |
9781482273557 |
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1482273551 |
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9780824797645 |
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0824797647 |
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