| Description |
1 online resource (1, 410 pages) : illustrations (some color) |
| Contents |
Type I interferons : genetics and structure / Shamith A. Samarajiwa, William Wilson, Paul J. Hertzog -- Activation of interferon gene expression through toll-like receptor-dependent and -independent pathways / Peyman Nakhaei, Suzanne Paz, John Hiscott -- Interferon proteins: structure, production and purification / Dimitris Platis, Graham R. Foster -- Interferon-[gamma] : gene and protein structure, transcription regulation, and actions / Ana M. Gamero, Deborah L. Hodge, David M. Reynolds, Maria Cecilia Rodriguez-Galan, Mansour Mohamadzadeh, Howard A. Young -- Interferon and related receptors / Sidney Pestka, Christopher D. Krause -- Type III interferons: the interferon-[lambda] family / Sergei V. Kotenko, Raymond P. Donnelly -- Biological actions of type I interferons / Melissa M. Brierley, Jyothi Kumaran, Eleanor N. Fish -- Interferons and apoptosis : recent developments / Michael J. Clemens, Ian W. Jeffrey -- Viral defense mechanisms against interferon / Santanu Bose, Amiya K. Banerjee -- Overview of clinical applications of type I interferons / Frank Müller -- Clinical applications of interferon-[gamma] / Christine W. Czarniecki, Gerald Sonnenfeld -- Measurement of interferon activities / Tony Meager -- The development and measurement of antibodies to interferon / Sidney E. Grossberg, Yoshimi Kawade |
| Summary |
At long last, the first book to cover all important areas of interferon science in one volume. Top scientists, including many pioneers in the field, highlight the role of interferons as research tools and as therapeutic agents in clinical applications. Edited by an experienced interferonologist, chapters include discussions of interferon genes, Type I, II and III IFNs, as well as their induction, production and purification, receptors actions, measuring IFN activities and anti-IFN antibodies, as well as the evolution of viral defense mechanisms. For immunologists, cancer researchers, medicinal |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Interferon -- Testing.
|
|
Interferon -- Therapeutic use.
|
|
Interferon.
|
|
Interferons.
|
| Form |
Electronic book
|
| Author |
Meager, Anthony.
|
|
John Wiley & Sons.
|
| ISBN |
3527311807 (print edition) |
|
3527607927 (electronic bk.) |
|
3527608206 (electronic bk.) |
|
9783527311804 (print edition) |
|
9783527607921 (electronic bk.) |
|
9783527608201 (electronic bk.) |
|
