A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1)
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1)
Insulin -- Synthesis -- Congresses. : Insulins, growth hormone, and recombinant DNA technology / editor, John L. Gueriguian ; associate editors, Henry I. Miller ... [and others]
Insulin -- therapeutic use [MESH] : Coping with life on insulin : a guide to insulin-dependent diabetes / Judith M. Steel, Margaret Dunn ; with a foreword by Arnold Bloom
1987
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Insulin -- Therapeutic use -- Standards. : National standards for the development and quality assessment of services initiating insulin therapy in the ambulatory setting