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Title Combating the threat of pandemic influenza : drug discovery approaches / edited by Paul F. Torrence
Published Hoboken, N.J. : Wiley-Interscience, [2007]


Location Call no. Vol. Availability
 W'PONDS  616.203061 Tor/Ctt  AVAILABLE
Description xiii, 279 pages, 12 unnumbered pages of plates : illustrations (some color) ; 25 cm
Contents Existing influenza antivirals: their mechanisms of action and potential in the face of avial influenza / Erik De Clercq -- Development of high-throughput screening assays for influenza / Diana L. Noah, E. Lucile White, and James W. Noah -- Mechanisms of IFN resistance by influenza virus / Heather J. Ezelle and Bret A. Hassel -- Broadly effective anti-respiratory virus agents / Shiro Shigeta -- Current status on development of nucleic acid-based antiviral drugs against influenza virus infection / Jonathan P. Wong ... [et al.] -- Antiviral RNA interference strategies targeting influenza virus and other respiratory viruses / Joost Haasnoot and Ben Berkhout -- Promising antiviral glyco-molecules from an edible algae / Toshimitsu Hayashi ... [et al.] -- Rational design of an anti-adhesion drug for influenza / Nicolai V. Bovin and Alexandra S. Gambaryan -- Understanding influenza neuraminidase inhibitors using quantitative structure-activity relationship (QSAR) models / Rajeshwar P. Verma and Corwin Hansch -- Peptide inhibitors targeting virus-cell fusion in Class 1 enveloped viruses / George F. Gao -- Novel influenza therapeutics / Laura M. Aschenbrenner
Summary "This guide gets readers up to speed on the latest advances and technologies in diverse approaches to drug discovery, covering: existing antivirals, including broadly effective anti-respiratory virus agents; the development of high-throughput screening assays; IFN resistance; the development of nucleic acid-based antiviral drugs; antiviral RNAi strategies targeting influenza virus; and other promising antiviral drug discovery strategues." "Combating the Threat of Pandemic Influenza: Drug Discovery Approaches consolidates the latest information on diverse approaches into one comprehensive resource. It is a hands-on reference for researchers in medicinal chemistry, pharmaceutical chemistry, drug discovery, biochemistry, virology and microbiology and public health."--BOOK JACKET
Bibliography Includes bibliographical references and index
Subject Antiviral agents.
Influenza -- Chemotherapy.
Influenza, Human -- drug therapy.
Influenza, Human -- prevention & control.
Antiviral Agents -- therapeutic use.
Disease Outbreaks -- prevention & control.
Drug Design.
Influenza Vaccines -- therapeutic use.
Author Torrence, Paul F.
LC no. 2007011326
ISBN 9780470118795 cloth
0470118792 cloth