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Title Immunoregulation in inflammatory bowel diseases : current understanding and innovation : proceedings of the Falk Symposium 153 held in Berlin, Germany, May 6-7, 2006 / edited by A. Dignass [and others]
Published Dordrecht : Springer, 2007

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Description 1 online resource (xv, 210, [6] pages) : illustrations
Series Falk symposium ; 153
Falk symposium ; 153
Contents Advances in the pathogenesis of inflammatory bowel disease -- Innate immune responses in inflammatory bowel disease -- The adaptive immune responses in inflammatory bowel disease -- Relevance of bacteria in the pathogenesis of inflammatory bowel disease -- Taking a toll on MD-2 in inflammatory bowel disease -- Optimization in therapy through improved disease classification? -- Classification of inflammatory bowel disease can only be based on the clinical phenotype -- Use of serology and genetics to differentiate inflammatory bowel disease phenotypes -- Do biomarkers help to optimize therapy in inflammatory bowel disease? -- Role of pharmacogenetics in the management of inflammatory bowel diseases -- Conventional immunomodulator therapy -- State-of-the-art therapy in accordance with guidelines -- Increased risk of morbidity associated with immunomodulatory treatment in patients with inflammatory bowel diseases -- Can immunomodulatory therapy be improved by metabolite measurement and combination therapy? -- Relevance of biologics -- Top-down therapy for inflammatory bowel disease -- step-up versus top-down strategies in inflammatory bowel disease what do we know in 2006? -- Importance of mucosal healing in Crohns disease and ulcerative colitis -- State-of-the-Art Lecture: Distinct antibacterial-defensin deficiencies in small intestinal and colonic Crohns disease -- New therapeutic approaches (Part I) -- Oligonucleotides new therapeutic approaches -- Probiotics in inflammatory bowel disease -- Helminth ova therapy for inflammatory bowel disease -- Retarded release phosphatidylcholine: a new therapeutic option for ulcerative colitis -- Topical steroids rectal application -- New therapeutic approaches (Part II) -- Apheresis -- The evolving understanding and therapy ofCrohns disease: innate immunity and sargramostim (GM-CSF) -- Immunosuppression with tacrolimus, everolimus and sirolimus -- T-cell modulating antibodies in inflammatory bowel disease
Summary Significant scientific progress has been made in recent years in the aetiopathogenesis of chronic inflammatory bowel diseases (IBD), that has changed or will change in the future the diagnostic and therapeutic approach in these diseases. The relevance of classical conventional IBD therapies has been critically re-evaluated under criteria of evidence-based medicine approaches. On the other hand, new therapeutic options have emerged. These include modern immunomodulators, biologics, probiotics, worm eggs and extracorporeal therapies. The clinical relevance of these new modalities is often difficult to assess for physicians who do not work frequently with IBD patients. This book, the proceedings of the Falk Symposium No.153 on Immunoregulation in Inflammatory Bowel Diseases Current Understanding and Innovation, held May 67, 2006 in Berlin, Germany, critically discusses established and emerging new concepts in the diagnosis and treatment of IBD, reflecting the recent advancements in the aetiopathogenesis of these diseases. Controversial problems, such as the optimal therapeutic strategy (step-up versus top-down), therapy-associated side-effects and optimal control and selection of IBD therapies, are addressed by an internationally-renowned team of authors. The book will be essential reading for both basic scientists and clinicians
Bibliography Includes bibliographical references and index
Subject Inflammatory bowel diseases -- Congresses
Inflammatory bowel diseases.
Inflammatory Bowel Diseases
Inflammatory Bowel Diseases -- immunology
Inflammatory bowel diseases
Genre/Form proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Dignass, A
Falk Symposium (153rd : 2007 : Berlin, Germany)
ISBN 9781402058882
1402058888
9781402058899
1402058896