Title Effects of immune cells and inflammation on smooth muscle and enteric nerves / editors, William J. Snape, Jr., Stephen M. Collins

Published Boca Raton, Fla. : CRC Press, ©1991

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Description 1 online resource (376 pages) : illustrations Summary This book provides the first comprehensive review of research that addresses the immunomodulation of gastrointestinal motility. Results from this new field of research are important for understanding motility disturbances and symptom-generation in a variety of clinical gastroenterological problems, including ulcerative colitis, Crohn's disease, enteric infections, and food allergies. The book provides overviews on current perspectives regarding the nature of inflammatory processes, inflammatory mediators, and other immune factors. It also describes a variety of experimental approaches that have been used to study the interactions between immune cells and smooth muscle or enteric nerves. The approaches include in vivo, as well as in vitro studies. Researchers involved in the general field of immunophysiology, as well as the more specific fields of gastrointestinal motility and inflammatory bowel diseases will find this book to be invaluable in their research Notes Papers from a workshop held in Montecito, Calif. on Mar. 25-28, 1990 Bibliography Includes bibliographical references and index Notes William J. Snape, Jr., M.D., is Chief of the Division of Gastroenterology in the Department of Medicine at Harbor-UCLA Medical Center and Professor of Medicine at the UCLA School of Medicine. Dr. Snape received his B.A. degree from Princeton University, Princeton, New Jersey in 1965 and his M.D. degree from Jefferson Medical College in 1969. He took his internal medicine residency training at the Bronx Municipal Medical Center and a post-doctoral fellowship in gastroenterology at the University of Pennsylvania. Dr. Snape was an Assistant and Associate Professor of Medicine at the University of Pennsylvania from 1975 to 1982. He assumed his present position in 1982. Dr. Snape is a member of the American Gastroenterological Association, American College of Gastroenterology, American Society for Gastrointestinal Endoscopy, and the American Society for Clinical Investigation. Dr. Snape has been the recipient of research grants from the National Institutes of Health, and the National Foundation for Ileitis and Colitis. He has published more than 150 papers on the pathophysiologic controls of gastrointestinal smooth muscle. His current research interests relate to the effect of inflammation on smooth muscle contractility. Stephen M. Collins, M.B.B.S., F.R.C.P. (U.K.), F.R.C.P. (C) obtained his medical degree at University College, London and at Westminster Hospital Medical School in London, England in 1971. He obtained postgraduate clinical training in England and at McMaster University in Canada where he subspecialized in gastroenterology. He obtained research training at the Digestive Diseases Branch of the National Institutes of Health (NIH) in Bethesda, Maryland between 1978 and 1981. His research interests originated in the study of the control of gastrointestinal motility and the effect of gastrointestinal hormones. He obtained training in cell biology at NIH and applied this to develop a preparation of single smooth muscle cells to study excitation-contraction coupling in gut muscle. Since becoming the Director of Intestinal Diseases Research Unit at McMaster, he has become interested in the ability of cells of the immune system to alter structure and function in smooth muscle and enteric nerves. The Intestinal Disease Research Unit, of which Dr. Collins is the Director, adopts an interdisciplinary and integrated approach to study the response of the gastrointestinal tract injury in general, and to inflammatory processes in particular; the work presented in this volume by Dr. Collins and some of his colleagues from McMaster reflects this research philosophy. Dr. Collins is a Fellow of the Royal College of Physicians of London, England, and a Fellow of the Royal College of Physicians and Surgeons of Canada, and is a Professor of Medicine at McMaster University Print version record Subject Gastrointestinal system -- Pathophysiology -- Congresses Smooth muscle -- Inflammation -- Congresses Nerves -- Inflammation -- Congresses Gastrointestinal system -- Motility -- Disorders -- Immunological aspects -- Congresses Gastrointestinal system -- Innervation -- Congresses Gastrointestinal system -- Motility. Cellular immunity. Inflammation. Smooth muscle. Gastrointestinal system -- Pathophysiology -- Congresses Inflammation -- Congresses Gastrointestinal system -- Innervation -- Congresses Gastrointestinal Diseases -- immunology Gastrointestinal Diseases -- physiopathology Gastrointestinal Motility Immunity, Cellular Inflammation Intestine, Small -- innervation Muscle, Smooth MEDICAL -- General. MEDICAL -- Clinical Medicine. SCIENCE -- Life Sciences -- Cytology. Smooth muscle Inflammation Gastrointestinal system -- Motility Cellular immunity Gastrointestinal system -- Innervation Gastrointestinal system -- Pathophysiology Smooth muscle -- Inflammation Genre/Form proceedings (reports) Conference papers and proceedings Conference papers and proceedings. Actes de congrès. Form Electronic book Author Snape, William J. Collins, Stephen M. ISBN 9780367813024 0367813025 9781000721881 1000721884 1000714063 9781000717976 1000717976 9781000714067

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