| Description |
1 online resource |
| Series |
Oxford medical histories |
|
Oxford medical histories.
|
| Contents |
Cover; The Antibody Molecule; Copyright; Dedication; Contents; Abbreviations; 1 Antibody pre-history: The emergence of empirical immunology; 2 Pre-molecular immunology: The dawn of mechanism; 3 Structural chemistry: Locks, keys, and colloids; 4 The foundations of antibody-antigen recognition emerge; 5 The cellular reformation; 6 The molecular path unfolds; 7 Uncovering the origins of antibody diversity; 8 Immunoglobulin constant regions; 9 Effector functions of constant regions; 10 Transmission and catabolism of IgG; 11 The structural context of antibody diversity |
|
12 Monoclonal antibodies and the mechanisms of hypermutation13 Antibody structure prediction and development of humanization strategies ; 14 Antibody engineering: Improving on natural immunity; 15 Therapeutic antibodies: Case study I: Prevention of respiratory syncytial virus illness; 16 Therapeutic antibodies: Case study II: Targeting breast cancer; 17 Antibodies: The therapeutic future; Author Index; Subject Index |
| Summary |
'The Antibody Molecule' follows the extraordinary journey of the medics and scientists who shaped the course of medical advances in the field of immunology which has seen chemists, physicists and biologists alike seeking to unravel the most complex system in the human body outside the brain. This title charts its intriguing history, from the genetic basis of antibody diversity to breakthroughs in crystallography and the exploitation of immunoglobulins as therapeutic platforms to treat cancer, inflammation and allergy |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Immunoglobulins.
|
|
Immunology -- History
|
|
Immunoglobulins
|
|
SCIENCE -- Life Sciences -- Anatomy & Physiology.
|
|
Immunoglobulins
|
|
Immunology
|
| Genre/Form |
History
|
| Form |
Electronic book
|
| ISBN |
9780191016158 |
|
0191016152 |
|
