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Title Fundamental immunology / editor, William E. Paul
Edition 6th ed
Published Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, ©2008


Description 1 online resource (xviii, 1603 pages, 16 unnumbered pages of plates) : illustrations (some color)
Series LWW medical book collection
Contents Section I: Introduction -- The immune system / William E. Paul
Section II: Organization and evolution of the immune system -- Lymphoid tissues and organs / Eitan M. Akirav, Shan Liao, and Nancy H. Ruddle -- Evolution of the immune system / Martin F. Flajnik and Louis Du Pasquier
Section III: Immunoglobulins and B lymphocytes -- Immunoglobulins: structure and function / Harry W. Schroeder, Jr., David Wald, and Neil S. Greenspan -- Antigen-antibody interactions and monoclonal antibodies / Jay A. Berzofsky, Ira J. Berkower, and Suzanne L. Epstein -- Immunoglobulins: molecular genetics / Edward Max -- B lymphocyte development and biology / Richard R. Hardy -- B lymphocyte signaling mechanisms and activation / Anthony L. DeFranco -- B lymphocyte biology / Michael McHeyzer-Williams
Section IV: T lymphocytes -- T cell antigen receptors / Mark M. Davis and Yueh-Hsiu Chien -- T lymphocyte signaling mechanisms and activation / Gary A. Koretzky -- Development of T cells / Ellen V. Rothenberg and Mary A. Yui -- Peripheral T lymphocyte responses and function / Steven L. Reiner
Section V: The intersection of innate and adaptive immunity -- The innate immune system / Ruslan Medzhitov -- Dendritic cells / Muriel Moser -- Natural killer cells / Wayne M. Yokoyama -- NKT cells and other innatelike T and B lineages / Albert Bendelac -- Macrophages and phagocytosis / Siamon Gordon -- Major histocompatibility complex (MHC) molecules: structure, function, and genetics / David H. Margulies [and others] -- Cell biology of antigen processing and presentation / Lélia Delamarre and Ira Mellman
Section VI: Regulation and effector functions of the immune response -- Immunogenicity and antigen structure / Jay A. Berzofsky and Ira J. Berkower -- Fc receptors and their role in immune regulation and inflammation / Jeffrey V. Ravetch and Falk Nimmerjahn -- Type I cytokines and interferons and their receptors / Warren J. Leonard -- Interleukin- 1 family of ligands and receptors / Charles A. Dinarello -- TNF-related cytokines in immunity / Carl F. Ware -- Chemokines / Philip M. Murphy -- Programmed cell death / Nicolas Bidère, Helen C. Su, and Michael J. Lenardo -- Immunologic memory / Stephen P. Schoenberger and Shane Crotty -- Immunologic tolerance / Ronald H. Schwartz -- Regulatory/suppressor T cells / Ethan M. Shevach -- The mucosal immune system / Hiroshi Kiyono [and others] -- Neural immune interactions / Jeanette I. Webster Marketon and Esther M. Sternberg -- Complement / Cornelia Speth [and others] -- Cytotoxic T lymphocytes / R. Chris Bleackley
Section VII: Immunity to infectious agents -- The immune response to parasites / David L. Sacks [and others] -- Immunity to viruses / Hildegund Ertl -- Immune responses to intracellular bacteria / Eric Pamer -- Immunity to extracellular bacteria / Jeffrey N. Weiser and Moon H. Nahm -- Immunology of HIV infection / Norman L. Letvin -- Vaccines / G.J.V. Nossal
Section VIII: Immunologic mechanisms in disease -- Systemic autoimmunity / Betty Diamond -- Organ-specific autoimmunity / Matthias G. von Herrath and Dirk Homann -- Immunological mechanisms of allergic disease / Marsha Wills-Karp -- Transplantation immunology / Megan Sykes, Kathryn Wood, and David H. Sachs -- Tumor immunology / Nicholas P. Restifo, Paul F. Robbins, and Steven A. Rosenberg -- Primary immunodeficiency diseases / Rebecca H. Buckley
Summary This title provides an overview of the rapidly expanding field of immunology, with bioscience information critical to understanding how the immune system functions. Insightful discussions describe the role the immune system plays in the prevention and pathogenesis of disease
Bibliography Includes bibliographical references and index
Notes Electronic version is available via Books@Ovid
Mode of access: World Wide Web
Print version record
Subject Immunology.
Allergy and Immunology
Form Electronic book
Author Paul, William E.
LC no. 2008011406