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Book Cover

Title Human antibody therapeutics for viral disease / Scott K. Dessain, editor
Published Berlin : Springer Verlag, c 2008


Description 1 online resource (xi, 188 pages) : illustrations (some color)
Series Current topics in microbiology and immunology, 0070-217X ; 317
Current topics in microbiology and immunology ; 317. 0070-217X
Contents Therapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies / Z.Y. Keck [and others] -- Antibodies for HIV treatment and prevention: window of opportunity? / M. Huber [and others] -- Human monoclonal antibody and vaccine approaches to prevent human rabies / T. Nagarajan [and others] -- Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab / H. Wu [and others] -- The molecular basis of antibody protection against West Nile virus / E. Mehlhop [and others] -- Exploring the native human antibody repertoire to create antiviral therapeutics / S.K. Dessain [and others]
Summary Although the utility of human antibodies as medical therapeutics for cancer and immune diseases has been well-established, it is only beginning to be realized for the treatment of viral infectious diseases. Polyclonal immunoglobulins have long been used for some viral diseases, but they have limited potency and disease scope. It should theoretically be possible to create monoclonal or oligoclonal antibody preparations that capture the essential curative functions of the humoral immune response to viral pathogens, yet only a single humanized monoclonal antibody (pavilizumab) has been approved a
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Immunoglobulins.
Immunoglobulins -- Therapeutic use
Virus diseases -- Treatment
Virus diseases -- Chemotherapy.
Virus Diseases -- therapy
Antibodies -- therapeutic use
MEDICAL -- Immunology.
Immunoglobulins -- Therapeutic use.
Virus diseases -- Treatment.
Virus diseases -- Chemotherapy.
Virus Diseases -- therapy.
Antibodies -- therapeutic use.
Sciences de la vie.
Virus diseases -- Treatment
Immunoglobulins -- Therapeutic use
Virus diseases -- Chemotherapy
Form Electronic book
Author Dessain, Scott K.
ISBN 9783540721468