Comparative immunoglobulin genetics / edited by Azad K. Kaushik, DVM, DSc (Paris), and Yfke Pasman, PharmD, MSc, University of Guelph, Guelph, Ontario, Canada
Front Cover; About The Editors; Contents; List Of Contributors; List Of Abbreviations; Preface; Chapter 1 Variable Lymphocyte Receptor-based Adaptive Immunity In The Agnathan Sea Lamprey; Chapter 2 Agnathan Sea Lamprey Tetrapods; Chapter 3 The Immunoglobulin Genes Of Bats; Chapter 4 Marsupial And Monotreme Immunoglobulin Genetics; Chapter 5 Organization Of The Immunoglobulin Heavy- And Light-chain Loci In The Rat; Chapter 6 Generation Of The Antibody Repertoire In Rabbits: Role Of Gut-associated Lymphoid Tissues; Chapter 7 The Immunoglobulin Genes Of Domestic Swine
Chapter 8 Bovine Immunoglobulin Genetics: Novel Phylogenetic PerspectiveChapter 9 Informatic Tools For Immunoglobulin Gene Sequence Analysis; Back Cover
Summary
This contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine-other species than the traditional subjects of mice and humans-are relevant to antibody design and engineer
