Limit search to available items
Book Cover

Title The kidney in plasma cell dyscrasias / volume editor, Guillermo A. Herrera
Published Basel ; New York : Karger, 2007


Description 1 online resource (vi, 216 pages) : illustrations (some color)
Series Contributions to nephrology ; vol. 153
Contributions to nephrology ; v. 153.
Contents The kidney in plasma cell dyscrasias: a current view and a look at the future / Herrera, G.A. -- A history of the kidney in plasma cell disorders / Steensma, D.P., Kyle, R.A. -- Patholigic studies useful for the diagnosis and monitoring of plasma cell dyscrasias / Veillon, D.M., Cotelingam, J.D. -- Serum free light chains in the diagnosis and monitoring of patients with plasma cell dyscrasias / Mayo, M.M., Schaef Johns, G. -- Mechanisms of renal damage in plasma cell dyscrasias: an overview / Merlini, G., Pozzi, C. -- Proximal tubular injury in myeloma / Batuman, V. -- Paraproteinemic renal diseases that involve the tubulo-interstitium / Herrera, G.A., Sanders, P.W. -- The mesangium as a target for glomerulopathic light and heavy chains: pathogenic considerations in light and heavy chain-mediated glomerular damage / Keeling, J., Herrera, G.A. -- Immunoglobulin light and heavy chain amyloidosis AL/AH: renal pathology and differential diagnosis / Picken, M.M. -- Diversity and diversification of light chains in myeloma: the specter of amyloidogenesis by proxy / Gu, M., Wilton, R., Stevens, F.J. -- High-dose therapy in patients with plasma cell dyscrasias and renal dysfunction / Pineda-Roman, M., Tricot, G. -- Current and emerging views and treatments of systemic immunoglobulin light-chain (AL) amyloidosis / Comenzo, R.L
Summary In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of patients. Several chapters are devoted to various glomerulopathies associated with deposition of immunoglobulin light and heavy chains, including those associated with amyloidosis. The sequential events are pointed out, crucial steps and key molecules open to modulation or control are delineated, and therapeutic advances are highlighted. Although the emphasis is on the management of cases with renal involvement, a distinct focus on the diseases as a whole and their impact on patients' general health and prognosis has been maintained throughout the discussions. Using a translational approach to renal manifestations in patients with plasma cell dyscrasias / myelomas, this publication conveys a comprehensive state-of-the-art view of the subject. It is aimed at practicing renal pathologists, nephrologists, internists and hematologists, as well as at trainees and scientists working in these specialties
Bibliography Includes bibliographical references and indexes
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Plasma cell diseases -- Complications
Kidneys -- Diseases -- Immunological aspects
Amyloidosis -- Complications
Kidneys -- Diseases.
Kidney -- pathology
Immunoglobulin Light Chains
Kidney Diseases
MEDICAL -- Nephrology.
Kidneys -- Diseases -- Immunological aspects
Paraproteinämie -- Nierenkrankheit -- Aufsatzsammlung.
Nierenkrankheit -- Paraproteinämie -- Aufsatzsammlung.
Form Electronic book
Author Herrera, Guillermo A., MD.
S. Karger (Firm)
ISBN 9783318013979