Limit search to available items
Book Cover

Title Epigenetics of the immune system / edited by Dieter Kabelitz, Jaydeep Bhat
Published London, United Kingdom : Academic Press, [2020]


Description 1 online resource
Series Translational epigenetics series ; volume 16
Translational epigenetics series ; v. 16.
Contents Intro -- Epigenetics of the Immune System -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1: An introduction to immunology and epigenetics -- Development of immune cells -- Dynamics of the immune response -- Immunological memory -- Basic overview of epigenetic regulation -- Genome architecture at primary structure scale: Cis-regulation through DNA elements -- Genome architecture at secondary structure scale: Trans-regulation through chromatin packaging and nucleosome positioning
Genome architecture at tertiary structure scale: Long-range chromatic interactions and gene regulation within chromatin ter ... -- Posttranscriptional regulation of RNA expression -- Posttranslational modifications: Chromatin remodeling complexes and histones -- Posttranslational modifications: Nonhistone proteins -- Advancing technology and use of interdisciplinary approaches -- References -- Chapter 2: Plant epigenetics and the ̀intelligent ́priming system to combat biotic stress -- Introduction -- Plant DNA methylation -- De novo DNA methylation -- Maintenance DNA methylation
Histone modifications -- RNA-associated silencing -- Epigenetics of plant microbe interactions -- Epigenetics of plant insect interactions -- Epigenetics of immune system and memory in plants -- Plant epigenetics: Model plants and application in agriculture -- Somatic embryogenesis -- Heterosis -- Conclusions -- References -- Chapter 3: Understanding immune system development: An epigenetic perspective -- Introduction: An outline of the chapter -- Epigenetic modifications and their functional output
Transcriptional control of epigenetic modifications: From on/off to cycling of epigenetic modifications -- DNA methylation: The mark of silence -- Histone modifications: Key epigenetic drivers -- Interdependence of DNA and histone modifications -- Epigenetic modifications mediated by chromatin remodeling and noncoding RNA (ncRNA) -- Accessible chromatin: A prelude to transcription -- Poised state of a gene: Epigenetic modifications priming gene for activation -- Epigenetic mechanisms regulating immune cell development -- Epigenetic regulation during hematopoiesis
Development of innate immune cells: Regulation by epigenetic processes -- Development of natural killer (NK) cells -- ILC2 cell development -- Development of macrophages -- Development of dendritic cells -- Transcription factors and epigenetic mechanisms involved in DC development -- Epigenetic mechanisms in adaptive immune system -- B-cell development and differentiation-An epigenetic perspective -- Pro-B to pre-B cell commitment -- Pre-B to immature B cells-Formation of BCR -- Peripheral differentiation of B cells -- Role of epigenetic regulation in T cells
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from digital title page (viewed on July 27, 2020)
Subject Immunogenetics.
Immunogenetic Phenomena
Form Electronic book
Author Kabelitz, Dieter, editor.
Bhat, Jaydeep, editor
ISBN 0128179651