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Title Multichain immune recognition receptor signaling : from spatiotemporal organization to human disease / edited by Alexander B. Sigalov
Published New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2008


Description 1 online resource (xxvii, 357 pages) : illustrations (some color)
Series Advances in experimental medicine and biology ; v. 640
Advances in experimental medicine and biology ; v. 640.
Contents T-cell receptor / Jose M. Rojo, Raquel Bello and Pilar Portolés -- B-cell receptor / Randall J. Brezski and John G. Monroe -- FC receptors / Maree S. Powell and P. Mark Hogarth -- Natural killer cell receptors / Roberto Biassoni -- Platelet glycoprotein VI / Stephanie M. Jung and Masaaki Moroi -- Clustering models / Wolfgang W.A. Schamel and Michael Reth -- Segregation models / Elaine P. Dopfer [and others] -- Kinetic proofreading model / Byron Goldstein [and others] -- Serial triggering model / Jacob Rachmilewitz -- Conformational model / Ruth M. Risueño, Angel R. Ortiz, and Balbino Alarcón -- Permissive geometry model / Susana Minguet and Wolfgang W.A. Schamel -- Signaling chain homooligomerization (SCHOOL) model / Alexander B. Sigalov -- Visualization of cell-cell interaction contacts : synapses and kinapses / Michael L. Dustin -- Visualization of protein interactions in living cells / Tomasz Zal -- Immunogenicity in peptide-immunotherapy : from self/nonself to similar/dissimilar sequences / Darja Kanduc
Therapeutic application of transmembrane T and natural killer cell receptor peptides / Nicholas Manolios [and others] -- FC receptor targeting in the treatment of allergy, autoimmune diseases and cancer / Akira Nakamura, Tomohiro Kubo and Toshiyuki Takai -- Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease / Joseph R. Podojil, Danielle M. Turley, and Stephen D. Miller -- MHC and MHC-like molecules : structural perspectives on the design of molecular vaccines / Vasso Apostolopoulos, Eliada Lazoura and Minmin Yu -- SCHOOL model and new targeting strategies / Alexander B. Sigalov -- Immune receptor signaling, aging and autoimmunity / Anis Larbi, Tamas Fülöp and Graham Pawelec -- Viral pathogenesis, modulation of immune receptor signaling and treatment / Walter M. Kim and Alexander B. Sigalov
Bibliography Includes bibliographical references and index
Subject Immune recognition.
T cells -- Receptors.
Killer cells.
Cellular signal transduction.
Cell receptors.
Receptors, Immunologic
Models, Immunological
Signal Transduction
Receptors, Cell Surface
SCIENCE -- Life Sciences -- Anatomy & Physiology.
Sciences de la vie.
Cell receptors.
Cellular signal transduction.
Immune recognition.
Killer cells.
T cells -- Receptors.
Form Electronic book
Author Sigalov, Alexander B.
LC no. 2008025647
ISBN 9780387097886