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Title Hypertrophic cardiomyopathy / Srihari S. Naidu, editor
Edition Second edition
Published Cham : Springer, [2019]

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Description 1 online resource
Contents Intro; Foreword; Foreword to 2nd Edition; Preface; Preface to 2nd Edition; Contents; Contributors; 1: Hypertrophic Cardiomyopathy: ThePast, thePresent, andtheFuture; The Past; The Birth ofHCM; Sudden Death; Familial Occurrence; Elucidation ofPathophysiology; Dynamic andVariable Obstruction; The Present; Clinical Findings; Echocardiography; Treatment; Pharmacologic Therapy; Invasive Therapy; Prevention ofSudden Death; Genetics; The Future; Pathobiology; Therapy; References; 2: Natural History ofHypertrophic Cardiomyopathy; Introduction; Disease Progression andPenetrance
Prognosis andOutcomesMortality; Atrial Fibrillation andStroke; Advanced Heart Failure andEnd-Stage HCM; Outcomes inHypertrophic Cardiomyopathy Subgroups; Left Ventricular Outflow Tract Obstruction andMid-Ventricular Obstruction; Apical HCM; Future Directions; Posttest; References; 3: Pathology andPathophysiology; Introduction; Epidemiology; Gross Pathology (Figs. 3.2, 3.3, 3.4, 3.5, 3.6, and3.7); Apical Hypertrophic Cardiomyopathy; Endocardial andValvular Pathology (Figs. 3.5 and3.6); Microscopic Pathologic Features (Table3.1 andFig. 3.8); Fibrosis (Fig. 3.9)
Coronary Artery Abnormalities (Fig. 3.10)Histologic Findings ofMyomectomy Specimens; Pathophysiology; Familial Hypertrophic Cardiomyopathy; Posttest; References; 4: Approach toDiagnosis: Echocardiography; Introduction; M-Mode Echocardiography; Two-Dimensional Echocardiography; LV Hypertrophy; LV Systolic Function; Left Atrial Volume; Doppler Echocardiography; Left Ventricular Outflow Tract Obstruction; Color Doppler; Pulse Wave Doppler; Continuous Wave Doppler; Diastolic Function Evaluation; Tissue Doppler Imaging; Strain andStrain Rate Imaging; Stress Echocardiography andLVOT Provocation
Contrast EchocardiographyTransesophageal Echocardiogram; Diagnostic Caveats; Conclusions; Questions; References; 5: Cardiac MRI inDiagnosis andManagement; Introduction; General Principles ofCMR; MR Physical Principles; Instrumentation; Contrast Agents; MR Protocols andCardiovascular Applications; Absolute andRelative Contraindications; CMR Applications inHCM; Assessment ofLV Volumes, Mass, andFunction; Regional Morphology andFunctional Assessment; Asymmetric Septal Hypertrophy; Apical HCM; Atypical Presentations; Abnormal Papillary Muscle Morphology; Mitral Valve Anomalies
MR Tagging forStrain Analysis andT1 MappingMiscellaneous; Evaluation ofLV Outflow Tract Obstruction; Qualitative andQuantitative Assessment ofMitral Regurgitation; Myocardial Perfusion andDelayed Enhancement; Differential Diagnosis; Valvular Aortic Stenosis; Subaortic Membrane; Infiltrative Cardiomyopathies; Practical Implications; Future Directions; Questions; References; 6: Genetics ofHCM andRole ofGenetic Testing; Introduction; Genetic Basis ofHCM; Genetics andPrognosis inHCM; Role ofGenetic Testing inHCM; General Principles; Importance ofDetailed andAccurate Phenotyping
Summary This extensively updated edition provides a comprehensive review of hypertrophic cardiomyopathy, the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and oftentimes focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. This edition provides a practical approach, establishing evidence-based best practice for all scenarios
Notes Print version record
Subject Heart -- Hypertrophy.
Cardiomyopathy, Hypertrophic
Cardiomegaly
Heart -- Hypertrophy
Form Electronic book
Author Naidu, Srihari S., editor.
ISBN 9783319924236
3319924230
3319924222
9783319924229