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Author Roy, Darbeshwar

Title Biometrical genetics : analysis of quanitative variation / Darbeshwar Roy
Published Oxford, U.K. : Alpha Science International, ©2012

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Description 1 online resource
Contents 1. Genes, Chromosomes and Characters -- 1.1. The Gene -- 1.2. Biochemistry of the Gene -- 1.3. Chromosomes -- 1.4. Characters -- 1.5. Protein Synthesis -- References -- 2. Analysis of Qualitative Traits -- 2.1. Gene Action and Interaction -- 2.1.1. Dominance -- 2.1.2. Overdominance -- 2.1.3. Co-dominance -- 2.1.4. Multiple alleles -- 2.1.5. Epistasis or non-allelic interaction -- 2.2. Application of Laws of Probability -- 2.2.1. Application to cases of two or more genes -- 2.2.2. Types of probability -- 2.2.3. Binomial probability -- 2.2.4. Multinomial probability -- 2.3. Test of Goodness of Fit -- 2.3.1. Two factor segregation -- 2.3.2. Test of heterogeneity of families -- 2.3.3. Testing of independence -- 2.4. Experimental Size -- 2.4.1. Distinction between two hypotheses -- 2.5. Linkage and Pleiotrophy -- 2.5.1. Detection of linkage -- 2.5.2. Estimation of recombination frequency -- 2.5.3. Efficiency of different types of families -- 2.5.4. Factors affecting the recombination frequency -- 2.5.5. Pleiotropy -- 2.6. Extra Chromosomal Inheritance -- 2.6.1. Criterion for extra-chromosomal inheritance -- 2.6.2. Cell organelles -- 2.7. Sex-Determination -- 2.8. Expression of Qualitative Gene(s) -- 2.8.1. Penetrance and expressivity -- 2.9. Estimation of Gene Frequency -- 2.9.1. Incomplete dominance -- 2.9.2. Multiple alleles -- 2.10. Estimation of Genetic Diversity -- References -- 3. Analysis of Quantitative Traits -- 3.1. Theories of Quantitative Variability -- 3.2. Description of Normal Distribution Curve -- 3.2.1. Mean -- 3.2.2. Mode and median -- 3.2.3. Variance and covariance -- 3.2.4. Range -- 3.2.5. Skewness and kurtosis -- 3.3. Threshold Variability -- 3.4. Meristic Variability -- 3.5. Poisson Distribution -- 3.6. Modifications of Binomial and Poisson Distributions -- 3.6.1. Gamma distribution -- 3.6.2. Hypergeometric distribution -- 3.7. Biomodal and Multimodal Distributions -- References -- 4. Statistical Estimations, Tests, Models and Designs -- 4.1. Estimation and Inference -- 4.1.1. Methods of estimation -- 4.2. Test of Significance -- 4.2.1. Chi-square test -- 4.2.2. F-test -- 4.2.3. The t-test -- 4.2.4. Z-distribution -- 4.2.5. Relationship between different distributions -- 4.2.6. Non-central chi-square -- 4.2.7. Non-central F -- 4.3. Statistical Models and Expectation of Mean Squares -- 4.3.1. Fixed model -- 4.3.2. Random model -- 4.3.3. Mixed model -- 4.4. Experimental Designs and Calculation of Mean Squares -- 4.4.1. Randomized Complete Block Design (RBD) -- 4.4.2. Nested design -- 4.4.3. Cross-classified design -- 4.4.4. Factorial experiment -- 4.4.5. Analysis of co-variance -- 4.5. Correlation and Regression Analysis -- 4.5.1. Correlation coefficient -- 4.5.2. Regression analysis -- 4.5.3. Joint regression analysis -- 4.5.4. Multiple regression -- 4.5.5. Partial correlation and regression -- 4.5.6. Multiple correlation -- 4.6. Orthogonal Polynomial -- 4.7. Non-Parametric Statistics -- 4.8. Multivariate Analysis -- 4.8.1. Principal component analysis -- 4.8.2. Factor analysis -- 4.8.3. Canonical analysis -- 4.8.4. Discrimination and classification -- 4.8.5. Principal co-ordinate analysis -- 4.9. Growth Curves -- 4.9.1. Competition -- References -- 5. Analysis of Means -- 5.1. Scaling Tests -- 5.2. Estimation of Parameters -- 5.3. Epistasis or Non-allelic Interaction -- 5.4. Estimation of Coefficient of Dispersion -- 5.5. Concept of Average Effect of Gene -- 5.6. Other Models of Estimation of Genetic Effects -- 5.7. Detection of Epistasis by other Methods -- References
12.6. Triploids -- 12.7. Haploids -- 12.7.1. Production of haploids -- 12.7.2. Identification of haploids -- 12.7.3. Advantages and disadvantages -- 12.7.4. Biometrical genetics of haploids -- 12.8. Doubled Haploids -- 12.8.1. Analysis of means -- 12.8.2. Analysis of variances -- 12.8.3. Estimation of additive and additive additive interaction variances -- 12.8.4. Estimation of dominance variance and the degree of dominance -- 12.8.5. Linkage disequilibrium -- 12.8.6. Estimation of recombination value -- 12.8.7. Skewness and kurtosis -- 12.8.8. Estimation of number of effective factors -- 12.8.9. Covariances/correlation -- 12.8.10. Generation of deriving DH lines -- 12.8.11. Efficiency of DH method -- References -- 13. Competition -- 13.1. Definition and Types -- 13.2. Yield-Density Relationship -- 13.3. Mixture Diallels -- 13.4. Intergenotypic Competition -- 13.4.1. Estimation of a, bm and bd -- 13.4.2. Partitioning of C-values -- 13.5. Nature of the Underlying Genetical Control of Competition and Competitive Ability -- 13.6. Competition in Natural Population -- 13.7. Estimation of Outcrossing Rate -- 13.8. Detection of Competition -- References -- 14. Environmental Variation -- 14.1. Definition and Types -- 14.2. Estimation of Environmental Variation -- 14.3. Individual Plant Randomization -- 14.4. Sampling Variation -- 14.5. Other Experimental Designs -- 14.6. Estimation of Experimental Error -- 14.7. Augmented Design -- 14.8. Environmental Covariance -- References -- 15. Heritability -- 15.1. Definition and Types -- 15.2. Heritability a Characteristic of Population -- 15.3. Estimates of Heritability -- 15.4. Effect of G [×] E Interaction -- 15.5. Uses of Estimates of Heritability -- 15.6. Changing Estimates of Heritability -- 15.7. Problems in use of Estimate of Heritability -- References -- 16. Estimation of the Number of Effective Factors -- 16.1. Approaches to Estimation of Number of Genes -- 16.2. Chromosome Assay -- 16.3. Statistical Properties of Distribution -- 16.4. Estimate of k using Dominance Genetic Effect and Dominance Genetic Variance -- 16.5. Use of F2 Derived Generation Variances -- 16.6. Estimation of Number of Effective Factors in Random Mating Population -- 16.7. Genotype Assay -- 16.7.1. Theory -- 16.8. Use of Dihaploids in the Estimation of Number of genes -- 16.8.1. Use of range and genetical variance of an F1, F2 derived DH populations -- 16.8.2. Use of variances of F2-derived population -- 16.8.3. Genotype assay -- 16.9. Estimation of the Number of Effective Factors in Haploids -- 16.10. Method for Locating Genes -- References -- 17. Analysis of Skewness and Kurtosis -- 17.1. Genetical Causes of Skewness and Kurtosis -- 17.2. Information on Gene Action and Interaction -- 17.3. Estimation of Coefficients of Skewness and Kurtosis in Population of Pure Breeding Lines -- 17.4. Effects of Random Environmental Variation and Genotype Environment Interaction -- 17.5. Estimation of Skewness and Kurtosis in Dihaploid Population -- 17.6. Effect of Skewness on Selection -- References -- 18. Transformation of Scale -- 18.1. Tests of Non-normality -- 18.2. Relation of Variability to Mean -- 18.3. Scale Effect -- 18.4. Variance Stabilizing Transformation -- 18.5. Poisson Distribution -- 18.6. Binomial Distribution -- References -- 19. Genetic Structure of Population -- 19.1. The Hardy-Weinberg Equilibrium -- 19.1.1. Testing goodness of fit -- 19.1.2. Extension of H.W. equilibrium to cases of multiple alleles, sex-linked genes and polygenic inheritance -- 19.1.3. Sex-linked loci -- 19.1.4. Polygenic traits -- 19.2. Changes in Gene Frequency -- 19.2.1. Effects of non-random mating -- 19.2.2. Self-fertilization -- 19.2.3. Sib mating -- 19.2.4. Assortative mating -- 19.2.5. Negative assortative mating -- 19.3. Mutation -- 19.3.1. Balance between mutation and selection -- 19.4. Selection -- 19.4.1. Complete elimination of recessive homozygotes -- 19.4.2. Balance between selection and inbreeding -- 19.5. Competitive Selection -- 19.6. Migration -- 19.6.1. Balance between selection and migration -- 19.6.2. Models for studying the population structure -- 19.7. Drift -- 19.7.1. Effective population size -- 19.7.2. Random genetic drift in natural populations -- 19.8. The Founder Principle -- 19.9. Gametic Selection -- 19.10. Meiotic Drive -- 19.11. Genetic Load -- 19.11.1. Segregational load -- 19.11.2. Mutational load -- References -- 20. Selection Theory -- 20.1. Response to Selection -- 20.1.1. Selection differential -- 20.1.2. Response due to selection in tetraploid -- 20.2. Correlated Response -- 20.3. Path Analysis -- 20.3.1. Determination of residual variability -- 20.3.2. Path coefficient vs correlation coefficient -- 20.3.3. Application of path analysis -- 20.4. Yield and Yield Components -- 20.5. Types of Selection -- 20.5.1. Efficiency of different methods -- 20.5.2. Combined selection -- 20.6. Selection Criterion -- 20.6.1. Single trait selection -- 20.6.2. Multitrait selection -- 20.7. Comparison of Efficiency of Different Methods -- 20.8. Selection Limit -- 20.9. Natural Selection -- 20.9.1. Stabilizing selection -- 20.9.2. Directional selection -- 20.9.3. Disruptive selection -- References -- 21. QTL Analysis -- 21.1. QTL Analysis -- 21.1.1. Linkage between QTL and molecular marker -- 21.1.2. Mapping methods -- 21.2. Models for Estimating Genetic Effects of QTL -- 21.3. Mapping Populations -- 21.4. Population Size -- 21.5. Experimental Design -- 21.6. Mapping in Polyploids -- 21.6.1. Methods of linkage analysis -- 21.7. Genetic Mapping -- 21.8. Information from QTL Mapping -- 21.9. Comparative Mapping and Orthologous Poly Genes -- 21.10. Identification of Links between Genotype and Phenotype -- References -- 22. Matrix -- 22.1. Definition and Types -- 22.2. Matrix Operations -- 22.3. Dispersion Matrix -- 22.4. Orthogonal Matrix -- 22.5. Diagonalization of Matrix -- References -- 23. Problems in Biometrical Genetics
Bibliography Includes bibliographical references at the end of each chapters and index
Subject Biometry.
Plant genetics.
Human genetics -- Variation.
Biometry
Plants -- genetics
Genetic Variation
biometrics.
Human genetics -- Variation
Biometry
Plant genetics
Form Electronic book
ISBN 9781783322466
1783322462