| Description |
1 online resource (xi, 286 pages) : illustrations |
| Series |
Neuromethods, 1940-6045 ; 29 |
|
Neuromethods ; 29. 0893-2336
|
| Contents |
Gene tools to study neuronal apoptosis -- Detection of apoptotic or necrotic death in neuronal cells by morphological, biochemical, and molecular analysis -- Detection of cell death in neural tissue and cell culture -- Cultured cerebellar granule neurons as a model of neuronal apoptosis -- Optimization and validation of RT-PCR as a tool to analyze gene expresion during apoptosis -- p53 induction is a marker of neuronal apoptosis -- Apoptosis and ischemia in the central nervous system -- Analyses of apoptosis-associated DNA fragmentation in vivo during neurodegeneration of the peripheral olfactory system in adult mammals -- Both irreversible neuronal death and reversible neuronal stress are associated with increased levels of statin, a marker of cell cycle arrest -- Beta-amyloid-induced neuronal cell death in transgenic mice and alzheimer's disease -- Use of TUNEL to measure retinal ganglion cell apoptosis -- Methods for detection of apoptosis in the CNS -- Techniques for distinguishing apoptosis from necrosis in cerebrocortical and cerebellar neurons -- The nematode Caenorhabditis elegans as a model system to study neuronal cell death |
| Summary |
Annotation "In Apoptosis Techniques and Protocols leading experts offer investigators at all levels of experience an indispensable introduction to the basics of apoptosis, as well as essential details of the methods used in its study. These authorities cover such important topics as the histological, biological, and molecular criteria for apoptosis and programmed cell death; necrosis and apoptosis in the CNS; and cellular, invertebrate, animal, and human models of apoptosis in Alzheimer's disease, AIDS, and stroke. The techniques they describe examine the critical steps involved in the apoptotic process, and include PCR analysis of cell-cycle-regulated proteins, histochemical analysis of DNA regulation, DNA laddering analysis, and cytochemical alterations of living cells."--BOOK JACKET. Title Summary field provided by Blackwell North America, Inc. All Rights Reserved |
| Analysis |
apoptose |
|
apoptosis |
|
celbiologie |
|
cellular biology |
|
Cellular Biology |
|
Celbiologie |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Title from title screen (viewed October 3, 2007) |
| Subject |
Apoptosis.
|
|
Necrosis.
|
|
Apoptosis -- physiology
|
|
Brain Diseases -- physiopathology
|
|
Histocytological Preparation Techniques
|
|
Necrosis
|
|
Neurons -- physiology
|
|
Apoptosis
|
|
Necrosis
|
|
Apoptosis
|
|
Celdood.
|
|
Fisiopatologia.
|
| Genre/Form |
Laboratory manuals
|
|
Laboratory manuals.
|
|
Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Poirier, Judes.
|
| ISBN |
9781592596348 |
|
1592596347 |
|
0896034518 |
|
9780896034518 |
|
9781592596355 |
|
1592596355 |
|
1280837179 |
|
9781280837173 |
|
9786610837175 |
|
6610837171 |
|
