Description |
1 online resource : illustrations |
Series |
Target organ toxicology series |
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Target organ toxicology series.
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Contents |
Cover; Half Title; Title Page; Copyright Page; Table of Contents; Contributors; Preface; Part I: Characterization of Chemical-Induced Hepatotoxicity; 1: Drug-Induced Hepatic Disease; 2: Morphologic Characteristics of Chemical-Induced Hepatotoxicity in Laboratory Rodents; 3: Chemical-Induced Hepatocarcinogenesis; Part ll: Mechanisms of Hepatotoxicity; 4: An Overview of Peroxisome Proliferation; 5: Acetaminophen-Induced Hepatotoxicity; 6: Evaluation of Chemical-Induced Oxidative Stress as a Mechanism of Hepatocyte Death; 7: Lipid Peroxidation as a Mediator of Chemical-Induced Hepatocyte Death |
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8: Immunologic Mediation of Chemical-Induced Hepatotoxicity9: The Role of Nonparenchymal Cells and Inflammatory Macrophages in Hepatotoxicity; Part III: Cholestasis; 10: Cholestatic Properties of Steroid Glucuronides; 11: Mechanisms Involved in Bile Acid-Induced Cholestasis; 12: Cholestasis Produced by Combinations of Manganese and Bilirubin; 13: Evaluation of Chemical-Induced Bile Duct Proliferation; Index |
Summary |
"This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, microscopic characteristics of the mechanisms by which chemicals can produce liver injury and experimental models useful for the study of liver dysfunction."--Provided by publisher |
Bibliography |
Includes bibliographical references and index |
Notes |
Vendor-supplied metadata |
Subject |
Hepatotoxicology.
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Poisoning.
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Liver -- drug effects
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Poisoning
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Hepatotoxicology
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Gastroenterology
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Toxicology
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Toxicologie.
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Hepatotoxemie.
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Lever.
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Cholestase.
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Form |
Electronic book
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Author |
Plaa, Gabriel L., editor
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Hewitt, William R., editor
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ISBN |
9781439810446 |
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1439810443 |
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