Description |
1 online resource (xvii, 360 pages) : illustrations (some color) |
Contents |
Hepatitis C virus infection and the role of the immune system -- Cryoglobulinemia: immunochemical characterization, serological abnormalities and histopathological changes -- Structural and genetic features, cytokines and chemokines in cryoglobulinemia -- Cellular compartments of HCV infection (and replication) -- Mechanism(s) of cryoprecipitation -- Clinical manifestations of cryoglobulinemia -- HCV infection, cryoglobulinemia and non-Hodgkin's lymphomas -- Therapy of cryoglobulinemia |
Summary |
The first observation of cold-induced precipitation of serum proteins dates back to 1933, when Wintrobe and Buell first described an unusual case of multiple myeloma in a woman whose serum reversibly precipitated at cold temperatures. In 1947, Lerner and Watson showed cold-precipitable proteins to be gammaglobulins and called them 'cryoglobulins' and the corresponding clinical condition 'cryoglobulinemia'. Meltzer and Franklin in 1966 provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia, showed that they consisted of two different globulin componen |
Analysis |
Emerging infectious diseases |
Bibliography |
Includes bibliographical references and index |
Subject |
Hepatitis C.
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Cryoglobulinemia.
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Cryoglobulinemia
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Hepatitis C
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MEDICAL -- Hepatology.
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Médecine.
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Cryoglobulinemia
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Hepatitis C
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Form |
Electronic book
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Author |
Dammacco, Franco
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ISBN |
9788847017054 |
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884701705X |
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1283453576 |
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9781283453578 |
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8847017041 |
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9788847017047 |
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