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Author Lewis, Rowena Sue

Title Analysis of the Stat5 genes in zebrafish / by Rowena Sue Lewis
Published [Place of publication not identified] : [publisher not identified], 2006


Location Call no. Vol. Availability
 MELB  572.865 Lew/Aot  AVAILABLE
Description ix, 211 pages : illustrations ; 30 cm
Summary This dissertation identified and characterised a key genetic regulator called Stat5 using zebrafish. Up-regulation of Stat5 led to an increase in blood cells, indicative of pre-leukaemia, whilst down-regulation decreased these cells and caused other defects. This work shows that Stat5 is critical in blood cell maturation and early embryonic development
Notes Degree conferred 2007
Submitted to the School of Life and Environmental Sciences of the Faculty of Science and Technology, Deakin University
Thesis (Ph.D.)--Deakin University, Victoria, 2006
Bibliography Includes bibliographical references (pages 177-211)
Subject Gene expression.
Genetic regulation.
Hematopoietic system.
Genre/Form Academic theses.
Author Deakin University. Faculty of Science and Technology.
Deakin University. School of Life and Environmental Sciences